[HTML][HTML] Insight into endothelial cell-derived extracellular vesicles in cardiovascular disease: molecular mechanisms and clinical implications

X Wang, B He - Pharmacological Research, 2024 - Elsevier
The endothelium is crucial in regulating vascular function. Extracellular vesicles (EVs) serve
as membranous structures released by cells to facilitate intercellular communication through …

Atorvastatin-pretreated mesenchymal stem cell-derived extracellular vesicles promote cardiac repair after myocardial infarction via shifting macrophage polarization …

Y Ning, P Huang, G Chen, Y Xiong, Z Gong, C Wu, J Xu… - BMC medicine, 2023 - Springer
Abstract Background Extracellular vesicles (EVs) derived from bone marrow mesenchymal
stem cells (MSCs) pretreated with atorvastatin (ATV)(MSCATV-EV) have a superior cardiac …

Extracellular vesicles (EVs) in ischemic conditioning and angiogenesis: Focus on endothelial derived EVs

E Alfì, C Thairi, S Femmino, G Alloatti, F Moccia… - Vascular …, 2021 - Elsevier
During myocardial ischemia, timely reperfusion is critical to limit infarct area and the overall
loss of cardiac contractile function. However, reperfusion further exacerbates the damage of …

Identifying plasma proteomic signatures from health to heart failure, across the ejection fraction spectrum

K Andrzejczyk, S Abou Kamar, AM van Ommen… - Scientific Reports, 2024 - nature.com
Circulating proteins may provide insights into the varying biological mechanisms involved in
heart failure (HF) with preserved ejection fraction (HFpEF) and reduced ejection fraction …

[HTML][HTML] Extracellular vesicles from patients with Acute Coronary Syndrome impact on ischemia-reperfusion injury

F D'Ascenzo, S Femmino, F Ravera, F Angelini… - Pharmacological …, 2021 - Elsevier
The relevance of extracellular vesicles (EV) as mediators of cardiac damage or recovery
upon Ischemia Reperfusion Injury (IRI) and Remote Ischemic PreConditioning (RIPC) is …

The influence of comorbidities on chemokine and cytokine profile in obstructive sleep apnea patients: preliminary results

M Chaszczewska-Markowska, K Górna… - Journal of Clinical …, 2023 - mdpi.com
Introduction: Obstructive sleep apnea (OSA) is frequently associated with a chronic
inflammatory state and cardiovascular/metabolic complications. The aim of this study was to …

Lymphatic and blood endothelial extracellular vesicles: a story yet to be written

J Trisko, J Fleck, S Kau, J Oesterreicher, W Holnthoner - Life, 2022 - mdpi.com
Extracellular vesicles (EVs), such as exosomes, microvesicles, and apoptotic bodies, are
cell-derived, lipid bilayer-enclosed particles mediating intercellular communication and are …

Platelet-derived extracellular vesicles encapsulate microRNA-34c-5p to ameliorate inflammatory response of coronary artery endothelial cells via PODXL-mediated …

X Bai, H Zhang, Z Li, O Chen, H He, X Jia… - Nutrition, Metabolism and …, 2022 - Elsevier
Background and aims Low-grade chronic inflammation was reported to serve as a distinctive
pathophysiologic feature of coronary artery disease (CAD), the leading cause of death …

Plasma-derived extracellular vesicles transfer microRNA-130a-3p to alleviate myocardial ischemia/reperfusion injury by targeting ATG16L1

S Yu, X Tang, T Zheng, S Li, H Ren, H Wu… - Cell and Tissue …, 2022 - Springer
Extracellular vesicles (EVs) are implicated in myocardial ischemia/reperfusion (I/R) injury as
modulators by shuttling diverse cargoes, including microRNAs (miRNAs). The current study …

Percutaneous coronary intervention (PCI) reprograms circulating extracellular vesicles from ACS patients impairing their cardio-protective properties

S Femminò, F D'Ascenzo, F Ravera, S Comità… - International Journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) are promising therapeutic tools in the treatment of
cardiovascular disorders. We have recently shown that EVs from patients with Acute …