Paracrine mechanisms of mesenchymal stem cells in tissue repair

M Gnecchi, P Danieli, G Malpasso… - Mesenchymal Stem Cells …, 2016 - Springer
Tissue regeneration from transplanted mesenchymal stromal cells (MSC) either through
transdifferentiation or cell fusion was originally proposed as the principal mechanism …

Spheroid culture of mesenchymal stem cells

Z Cesarz, K Tamama - Stem cells international, 2016 - Wiley Online Library
Compared with traditional 2D adherent cell culture, 3D spheroidal cell aggregates, or
spheroids, are regarded as more physiological, and this technique has been exploited in the …

Platelets facilitate the wound-healing capability of mesenchymal stem cells by mitochondrial transfer and metabolic reprogramming

J Levoux, A Prola, P Lafuste, M Gervais, N Chevallier… - Cell metabolism, 2021 - cell.com
Platelets are known to enhance the wound-healing activity of mesenchymal stem cells
(MSCs). However, the mechanism by which platelets improve the therapeutic potential of …

Biophysical and biochemical cues of biomaterials guide mesenchymal stem cell behaviors

J Li, Y Liu, Y Zhang, B Yao, Enhejirigala, Z Li… - Frontiers in Cell and …, 2021 - frontiersin.org
Mesenchymal stem cells (MSCs) have been widely used in the fields of tissue engineering
and regenerative medicine due to their self-renewal capabilities and multipotential …

[HTML][HTML] Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease

SH Ranganath, O Levy, MS Inamdar, JM Karp - Cell stem cell, 2012 - cell.com
The broad repertoire of secreted trophic and immunomodulatory cytokines produced by
mesenchymal stem cells (MSCs), generally referred to as the MSC secretome, has …

3D cell sheet structure augments mesenchymal stem cell cytokine production

S Bou-Ghannam, K Kim, DW Grainger, T Okano - Scientific reports, 2021 - nature.com
Mesenchymal stem cells (MSCs) secrete paracrine factors that play crucial roles during
tissue regeneration. An increasing body of evidence suggests that this paracrine function is …

Enhanced proliferation and differentiation of Oct4-and Sox2-overexpressing human adipose tissue mesenchymal stem cells

SM Han, SH Han, YR Coh, G Jang, J Chan Ra… - … & molecular medicine, 2014 - nature.com
Mesenchymal stem cells (MSCs) are attractive candidates for clinical repair or regeneration
of damaged tissues. Oct4 and Sox2, which are essential transcription factors for pluripotency …

Osteogenesis and bone remodeling: A focus on growth factors and bioactive peptides

S Toosi, J Behravan - Biofactors, 2020 - Wiley Online Library
Bone is one of the most frequently transplanted tissues. The bone structure and its
physiological function and stem cells biology were known to be closely related to each other …

[HTML][HTML] A simple and robust serum-free media for the proliferation of muscle cells

S Skrivergaard, JF Young, N Sahebekhtiari… - Food Research …, 2023 - Elsevier
Cultivated meat production requires an efficient, robust and highly optimized serum-free cell
culture media for the needed upscaling of muscle cell expansion. Existing formulations of …

A human epidermal growth factor-curcumin bandage bioconjugate loaded with mesenchymal stem cell for in vivo diabetic wound healing

C Mohanty, J Pradhan - Materials Science and Engineering: C, 2020 - Elsevier
Bone-marrow-derived mesenchymal stem cells (MSCs) are of growing interest for the
treatment of diabetic wound healing. However, they are often associated with poor …