Importance The magnitude and variability of cytokine alterations in depression are not clear.
Objective To perform an up to date meta-analysis of mean differences of immune markers in …

Predicting antidepressant treatment response has been a clinical challenge for major
depressive disorder (MDD). The inflammation hypothesis of depression suggests that …

Abstract Introduction Major Depressive Disorder (MDD) in accordance to the inflammatory
concept is associated with complex immunological disturbances in the central nervous …

Low-grade inflammation plays a role not only in the pathogenesis of major depressive
disorder (MDD) but probably also in the poor responsiveness to regular antidepressants …

Introduction Peripheral levels of inflammatory markers are elevated in major depressive
disorder (MDD). Selective serotonin reuptake inhibitors (SSRIs) affect levels of inflammatory …

Background: We previously found that a forest bathing (shinrin-yoku) program significantly
reduced the scores for depression, anxiety, anger, fatigue, and confusion and increased the …

Clinical evidence suggests that inflammation is a key factor to understand the causes of
depressive symptoms. Fluoxetine is one of the main first-line medications used for …

Introduction: Millions of people worldwide suffer from depression, but despite advances in
pharmacological therapies, many patients do not experience symptomatic remission or …

Raised pro-inflammatory immune/inflammatory setpoints, leading to an increased
production of peripheral cytokines, have been associated with Major Depressive Disorder …

Major depressive disorder (MDD) is one of the most prevalent mental illness and a leading
cause of disability worldwide. Despite a range of effective treatments, more than 30% of …