Despite advances in treating patients with melanoma, there are still many treatment
challenges to overcome. Studies with snake venom-derived proteins/peptides describe their …

The di-2-pyridylketone thiosemicarbazones demonstrated marked anticancer efficacy,
prompting progression of DpC to clinical trials. However, DpC induced deleterious oxy …

A series of thiosemicarbazones with the general formula, R− CHdouble bondN− NH− C (S)−
R 1 [R= C 6 H 5 F & R 1= C 4 H 9 NO (TL1), R= C 8 H 10 O 2 & R 1= C 4 H 9 NO (TL2), R= C …

Cancer is one of the major causes of death worldwide, and breast cancer is the most
prevalent and deadly type among women. Despite the side effects and the phenomena of …

A couple of N‐(4)‐morpholine/pyrrolidine‐substituted thiosemicarbazones (TSCs) of
fluorene‐2‐carboxaldehyde (FM and FP), and their corresponding thiadiazoles (TDZs)(CFM …

In the present study, nickel ferrite (NiFe2O4)-based smart magnetic nanoparticles were
fabricated and coated with methionine. Physiochemical characterization of the obtained Met …

Five novel cobalt complexes of pyridine-based heterocyclic thiosemicarbazones [Co (BpT)
2] Cl (1),[Co (BpT) 2](NO 3)·(H 2 O)(2),[Co (ApT) 2] Br·(CH 3 OH)(3),[Co (BpT) 2] Br (4) and …

Targeting DNA repair, like PARP-1 and TOPO-I, shows promise in cancer therapy. However,
resistance to single agents requires complex and costly combination strategies with …

A series of novel modifications were performed at the N (4) position of 5-hydroxyisatin
thiosemicarbazone (TSC). The structure–activity approach is applied to design and …

Thiosemicarbazones and their analogues are of significant interest due to their antiviral,
antibacterial and anticancer properties. Recent advancements in nanoparticle-based …