Multiplex profiling of developmental cis-regulatory elements with quantitative single-cell expression reporters
The inability to scalably and precisely measure the activity of developmental cis-regulatory
elements (CREs) in multicellular systems is a bottleneck in genomics. Here we develop a …
elements (CREs) in multicellular systems is a bottleneck in genomics. Here we develop a …
[HTML][HTML] Molecular basis of proton-sensing by G protein-coupled receptors
Three proton-sensing G protein-coupled receptors (GPCRs), GPR4, GPR65, and GPR68,
respond to changes in extracellular pH to regulate diverse physiology and are implicated in …
respond to changes in extracellular pH to regulate diverse physiology and are implicated in …
Scalable methods for genomic analysis of in vitro models of mammalian embryogenesis
SG Regalado - 2024 - search.proquest.com
Mammalian development, from the single-celled zygote to a multicellular individual, is an
incredible dynamic journey that is marked by many milestones measurable across many …
incredible dynamic journey that is marked by many milestones measurable across many …