Simple Summary Four-stranded nucleic acid secondary structures (quadruplexes) including
DNA G-quadruplexes, RNA G-quadruplexes and i-Motifs display key regulatory functions in …

The formation of G-quadruplex structures (G4s) in vitro from guanine (G)-rich nucleic acid
sequences of DNA and RNA stabilized with monovalent cations, typically K+ and Na+, under …

DNA G4-structures from human c-MYC promoter and telomere are considered as important
drug targets; however, the developing of small-molecule-based fluorescent binding ligands …

DNA is fundamentally important for all cellular organisms due to its role as a store of
hereditary genetic information. The precise and accurate regulation of gene transcription …

A series of new mitochondrial-selective fluorescent probe was designed and synthesized
based on the integration of two planar molecular scaffolds of benzo-indole/indole with a p …

Abstract G-quadruplex (G4) has become an essential target for the therapy of human genetic
diseases (cancer included) with important biological functions for regulation and monitoring …

The development of triple-negative breast cancer (TNBC) is highly associated with G-
quadruplex (G4); thus, targeting G4 is a potential strategy for TNBC therapy. Because …

DNA binding transcription factors possess the ability to interact with lipid membranes to
construct ion-permeable pathways. Herein, we present a thiazole-based DNA binding …

The development of site‐specific, target‐selective and biocompatible small molecule ligands
as a fluorescent tool for real‐time study of cellular functions of RNA G‐quadruplexes (G4s) …

In the past 10 years, many fluorescent probes have been developed to recognize G-
quadruplexes (G4s) since G4s play an important role in biological systems. However, the …