Mitochondria are highly dynamic intracellular organelles with ultrastructural heterogeneity
reflecting the behaviour and functions of the cells. The ultrastructural remodelling, performed …

Human embryonic stem cell (hESC)-derived midbrain dopaminergic (mDA) cell
transplantation is a promising therapeutic strategy for Parkinson's disease (PD). Here, we …

AIMS: Stem cells are a new hope to ameliorate impaired diabetic wound healing. The
purpose of this study was to evaluate the effect of adipose tissue derived mesenchymal stem …

There is a critical clinical need to develop therapies for nonhealing diabetic foot ulcers.
Topically applied mesenchymal stromal cells (MSCs) provide a novel treatment to augment …

Preclinical assessment of the therapeutic potential of dopamine (DA) neuron replacement in
Parkinson's disease (PD) has primarily been performed in the 6-hydroxydopamine toxin …

Incorporation of scaffolds has long been recognized as a critical element in most tissue
engineering strategies. However with regard to intervertebral disc tissue engineering, the …

Hyaluronic acid (HA) has received a lot of attention recently as a biomaterial with
applications in wound healing, drug delivery, vascular repair and cell and/or gene delivery …

Manual tracing of magnetic resonance imaging (MRI) represents the gold standard for
segmentation in clinical neuropsychiatric research studies, however automated approaches …

Collagen/calcium phosphate scaffolds have been used for bone reconstruction due to their
inherent similarities to the bone extracellular matrix. Calcium phosphate alone has also …

The physiological processes involved in tissue development and regeneration also include
the parallel formation of blood and lymphatic vessel circulations which involves their growth …