Bipolar disorder

I Grande, M Berk, B Birmaher, E Vieta - The Lancet, 2016 - thelancet.com
Bipolar disorder is a recurrent chronic disorder characterised by fluctuations in mood state
and energy. It affects more than 1% of the world's population irrespective of nationality …

Biological hypotheses and biomarkers of bipolar disorder

E Sigitova, Z Fišar, J Hroudová… - Psychiatry and …, 2017 - Wiley Online Library
The most common mood disorders are major depressive disorders and bipolar disorders
(BD). The pathophysiology of BD is complex, multifactorial, and not fully understood …

C-reactive protein is increased in schizophrenia but is not altered by antipsychotics: meta-analysis and implications

BS Fernandes, J Steiner, HG Bernstein, S Dodd… - Molecular …, 2016 - nature.com
The inflammatory hypothesis of schizophrenia (SZ) posits that inflammatory processes and
neural–immune interactions are involved in its pathogenesis, and may underpin some of its …

Peripheral brain-derived neurotrophic factor (BDNF) as a biomarker in bipolar disorder: a meta-analysis of 52 studies

BS Fernandes, ML Molendijk, CA Köhler, JC Soares… - BMC medicine, 2015 - Springer
Background The neurotrophic hypothesis postulates that mood disorders such as bipolar
disorder (BD) are associated with a lower expression of brain-derived neurotrophic factor …

The International Society for Bipolar Disorders Task Force report on pediatric bipolar disorder: Knowledge to date and directions for future research

BI Goldstein, B Birmaher, GA Carlson… - Bipolar …, 2017 - Wiley Online Library
Objectives Over the past two decades, there has been tremendous growth in research
regarding bipolar disorder (BD) among children and adolescents (ie, pediatric BD [PBD]) …

An updated meta-analysis of oxidative stress markers in bipolar disorder

NC Brown, AC Andreazza, LT Young - Psychiatry research, 2014 - Elsevier
Despite its debilitating symptoms, the pathophysiology of bipolar disorder (BD) remains
unclear. One consistently compelling finding, however, has been the presence of oxidative …

Peripheral brain-derived neurotrophic factor in schizophrenia and the role of antipsychotics: meta-analysis and implications

BS Fernandes, J Steiner, M Berk, ML Molendijk… - Molecular …, 2015 - nature.com
It has been postulated that schizophrenia (SZ) is related to a lower expression of brain-
derived neurotrophic factor (BDNF). In the past few years, an increasing number of divergent …

A systematic review of the association between psychiatric disturbances and endometriosis

CJ Pope, V Sharma, S Sharma… - Journal of Obstetrics and …, 2015 - Elsevier
Objective An association between endometriosis and psychiatric disturbances has been
identified by some researchers. The purpose of this systematic review was to consolidate …

The Bipolar Illness Onset study: research protocol for the BIO cohort study

LV Kessing, K Munkholm, M Faurholt-Jepsen… - BMJ open, 2017 - bmjopen.bmj.com
Introduction Bipolar disorder is an often disabling mental illness with a lifetime prevalence of
1%–2%, a high risk of recurrence of manic and depressive episodes, a lifelong elevated risk …

Bipolar disorder: role of immune-inflammatory cytokines, oxidative and nitrosative stress and tryptophan catabolites

G Anderson, M Maes - Current psychiatry reports, 2015 - Springer
Bipolar disorder (BD) is a complex disorder with a range of presentations. BD is defined by
the presentation of symptoms of mania or depression, with classification dependent on …