Heparan sulfate proteoglycans (HSPG) are composed of unbranched, negatively charged
heparan sulfate (HS) polysaccharides attached to a variety of cell surface or extracellular …

The rapid emergence of antimicrobial resistant strains to conventional antimicrobial agents
has complicated and prolonged infection treatment and increased mortality risk globally …

Interactions between nanoparticles and viruses have attracted increasing attention due to
the antiviral activity of nanoparticles and the resulting possibility to be employed as …

Recently, various types of cultured cells have been used to research the mechanisms of
transport and metabolism of drugs. Although many studies using cultured cell systems have …

Heparan sulfate proteoglycans (HSPGs) are cell surface receptors that are involved in the
cellular uptake of pathologic amyloid proteins and viruses, including the novel coronavirus; …

Introduction: Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract
infections (LRTI) in infants, the elderly, and the immunocompromised. Although the …

Microbial resistance to conventional antibiotics is one of the most outstanding medical and
scientific challenges of our times. Despite the recognised need for new anti-infective agents …

A new nanoparticulate system for foscarnet delivery was prepared and evaluated.
Nanoparticles were obtained by ionotropic gelation of chitosan induced by foscarnet itself …

Despite tremendous global efforts since the beginning of the COVID-19 pandemic, still only
a limited number of prophylactic and therapeutic options are available. Although vaccination …

Human metapneumovirus (HMPV), a recently discovered paramyxovirus, infects nearly
100% of the world population and causes severe respiratory disease in infants, the elderly …