Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine

H Luo, CT Vong, H Chen, Y Gao, P Lyu, L Qiu, M Zhao… - Chinese medicine, 2019 - Springer
Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer
activities, including anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects …

Reactive oxygen species and cancer paradox: to promote or to suppress?

S Galadari, A Rahman, S Pallichankandy… - Free Radical Biology …, 2017 - Elsevier
Reactive oxygen species (ROS), a group of highly reactive ions and molecules, are
increasingly being appreciated as powerful signaling molecules involved in the regulation of …

Gambogic acid as a candidate for cancer therapy: a review

Y Liu, Y Chen, L Lin, H Li - International Journal of Nanomedicine, 2020 - Taylor & Francis
Gambogic acid (GA), a kind of dry resin secreted by the Garcinia hanburyi tree, is a natural
active ingredient with various biological activities, such as anti-cancer, anti-inflammatory …

Hypoxia and selective autophagy in cancer development and therapy

I Daskalaki, I Gkikas, N Tavernarakis - Frontiers in cell and …, 2018 - frontiersin.org
Low oxygen availability, a condition known as hypoxia, is a common feature of various
pathologies including stroke, ischemic heart disease, and cancer. Hypoxia adaptation …

Multiple mechanisms of anti-cancer effects exerted by astaxanthin

L Zhang, H Wang - Marine drugs, 2015 - mdpi.com
Astaxanthin (ATX) is a xanthophyll carotenoid which has been approved by the United
States Food and Drug Administration (USFDA) as food colorant in animal and fish feed. It is …

Therapeutic potential of gambogic acid, a caged xanthone, to target cancer

K Banik, C Harsha, D Bordoloi, BL Sailo, G Sethi… - Cancer letters, 2018 - Elsevier
Natural compounds have enormous biological and clinical activity against dreadful diseases
such as cancer, as well as cardiovascular and neurodegenerative disorders. In spite of the …

Excess iron aggravates the severity of COVID-19 infection

GK Chaubey, R Dilawari, R Modanwal… - Free Radical Biology …, 2023 - Elsevier
Abstract Coronavirus disease-19 (COVID-19) can induce severe inflammation of the lungs
and respiratory system. Severe COVID-19 is frequently associated with hyper inflammation …

Autophagy in cancer stem cells: a potential link between chemoresistance, recurrence, and metastasis

R Ojha, S Bhattacharyya, SK Singh - BioResearch open access, 2015 - liebertpub.com
Cancer cells require an uninterrupted nutritional supply for maintaining their proliferative
needs and this high demand in concurrence with inadequate supply of blood and nutrition …

Dually enhanced phototherapy by gambogic acid and hyperthemia-activated chemotherapy for synergistic breast cancer treatment

Y Wang, C Yue, M Zhang, D Li, T Xu, M He… - Chemical Engineering …, 2023 - Elsevier
Combining chemotherapy and phototherapy (including photodynamic therapy and
photothermal therapy) via nanoscale drug delivery systems has been widely explored to …

Long noncoding RNA GAS5 promotes bladder cancer cells apoptosis through inhibiting EZH2 transcription

M Wang, C Guo, L Wang, G Luo, C Huang, Y Li… - Cell death & …, 2018 - nature.com
Aberrant expression of long noncoding RNA GAS5 in bladder cancer (BC) cells was
identified in recent studies. However, the regulatory functions and underlying molecular …