Atypical teratoid/rhabdoid tumor (AT/RT) is the most common malignant CNS tumor of
children below 6 months of age. The majority of AT/RTs demonstrate genomic alterations in …

Pediatric neuro-oncology has undergone an exciting and dramatic transformation during the
past 5 years. This article summarizes data from collaborative group and institutional trials …

Atypical teratoid/rhabdoid tumor (ATRT) is one of the most common brain tumors in infants.
Although the prognosis of ATRT patients is poor, some patients respond favorably to current …

Background Rhabdoid brain tumours, also called atypical teratoid rhabdoid tumours, are
lethal childhood cancers with characteristic genetic alterations of SMARCB1/hSNF5. Lack of …

Atypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant embryonal central nervous
system tumor commonly affecting children< 3 years of age. It roughly constitutes 1%–2% of …

Atypical teratoid rhabdoid tumors (AT/RT) are characterized by mutations and subsequent
inactivation of SMARCB 1 (INI 1, hSNF 5), a predilection for very young children and an …

Introduction Atypical teratoid rhabdoid tumor (ATRT) is a rare, often lethal brain tumor of
childhood characterized by a complex epigenetic landscape amongst a simple genetic …

Pediatric brain tumors are the second most common malignancy of childhood after acute
leukemia and the number one cause of cancer-related mortality 1. Over the past decade …

Atypical teratoid rhabdoid tumour (ATRT) is a malignant tumour of the central nervous
system with a dismal prognosis. There is no consensus on optimal treatment and different …

While 2/3 of patients with ATRT are less than 3 years at diagnosis, the literature suggests
younger children present with more aggressive disease and poorer outcome. However, little …