Satellite DNAs between selfishness and functionality: structure, genomics and evolution of tandem repeats in centromeric (hetero) chromatin

M Plohl, A Luchetti, N Meštrović, B Mantovani - Gene, 2008 - Elsevier
Satellite DNAs (tandemly repeated, non-coding DNA sequences) stretch over almost all
native centromeres and surrounding pericentromeric heterochromatin. Once considered as …

Cytogenetic screening of livestock populations in Europe: an overview

A Ducos, T Revay, A Kovacs, A Hidas… - … and genome research, 2008 - karger.com
Clinical animal cytogenetics development began in the 1960's, almost at the same time as
human cytogenetics. However, the development of the two disciplines has been very …

Satellite non-coding RNAs: the emerging players in cells, cellular pathways and cancer

D Ferreira, S Meles, A Escudeiro… - Chromosome …, 2015 - Springer
For several decades, transcriptional inactivity was considered as one of the particular
features of constitutive heterochromatin and, therefore, of its major component, satellite DNA …

Cat mammary tumors: Genetic models for the human counterpart

F Adega, A Borges, R Chaves - Veterinary sciences, 2016 - mdpi.com
The records are not clear, but Man has been sheltering the cat inside his home for over
12,000 years. The close proximity of this companion animal, however, goes beyond sharing …

FA-SAT is an old satellite DNA frozen in several Bilateria genomes

R Chaves, D Ferreira… - Genome biology and …, 2017 - academic.oup.com
In recent years, a growing body of evidence has recognized the tandem repeat sequences,
and specifically satellite DNA, as a functional class of sequences in the genomic “dark …

Satellite Noncoding RNAs (ncRNA) as Cancer Biomarkers? New Insights from FA-SAT ncRNA Molecular and Clinical Profiles in Feline Mammary Tumors

D Ferreira, M Soares, J Correia, F Adega… - Omics: a journal of …, 2022 - liebertpub.com
Satellite noncoding RNAs (ncRNAs) are a new frontier of cancer biology research and
biomarkers. While the knowledge on ncRNAs in human cancers is still limited, studies in …

Canine and feline spontaneous mammary tumours as models of human breast cancer

H Vilhena, AC Figueira, F Schmitt, A Canadas… - Pets as Sentinels …, 2020 - Springer
The frequency of cancer presents an increasing trend in humans and companion animals,
and despite recent advances in diagnosis and treatment, it remains a major cause of …

Cytogenomics of feline cancers: advances and opportunities

R Thomas - Veterinary Sciences, 2015 - mdpi.com
Relative to the dog, integration of the cat into the “One Health” concept has been more
restricted, particularly in the field of molecular oncology. Beyond the continual need to …

DNA Methylation Patterns of a Satellite Non-coding Sequence – FA-SAT in Cancer Cells: Its Expression Cannot Be Explained Solely by DNA Methylation

D Ferreira, A Escudeiro, F Adega, R Chaves - Frontiers in genetics, 2019 - frontiersin.org
Satellite ncRNAs are emerging as key players in cell and cancer pathways. Cancer-linked
satellite DNA hypomethylation seems to be responsible for the overexpression of satellite …

FA-SAT ncRNA interacts with PKM2 protein: depletion of this complex induces a switch from cell proliferation to apoptosis

D Ferreira, A Escudeiro, F Adega, SI Anjo… - Cellular and Molecular …, 2020 - Springer
FA-SAT is a highly conserved satellite DNA sequence transcribed in many Bilateria species.
To disclose the cellular and functional profile of FA-SAT non-coding RNAs, a comprehensive …