Spice drugs are more than harmless herbal blends: a review of the pharmacology and toxicology of synthetic cannabinoids

KA Seely, J Lapoint, JH Moran, L Fattore - Progress in Neuro …, 2012 - Elsevier
“K2” and “Spice” drugs (collectively hereafter referred to as Spice) represent a relatively new
class of designer drugs that have recently emerged as popular alternatives to marijuana …

Adverse effects of synthetic cannabinoids: management of acute toxicity and withdrawal

ZD Cooper - Current psychiatry reports, 2016 - Springer
Although several chemical structural classes of synthetic cannabinoids (SCs) were recently
classified as Schedule I substances, rates of use and cases of serious toxic effects remain …

Spicing things up: synthetic cannabinoids

M Spaderna, PH Addy, DC D'Souza - Psychopharmacology, 2013 - Springer
Rationale Recently, products containing synthetic cannabinoids, collectively referred to as
Spice, are increasingly being used recreationally. Objectives The availability, acute …

Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to Δ9-THC: mechanism underlying greater toxicity?

WE Fantegrossi, JH Moran, A Radominska-Pandya… - Life sciences, 2014 - Elsevier
K2 or Spice products are emerging drugs of abuse that contain synthetic cannabinoids
(SCBs). Although assumed by many teens and first time drug users to be a “safe” and “legal” …

Synthetic cannabinoids—further evidence supporting the relationship between cannabinoids and psychosis

L Fattore - Biological psychiatry, 2016 - Elsevier
Consumption of synthetic mind-altering compounds, also known as “new psychoactive
substances,” is increasing globally at an alarming rate. Synthetic cannabinoids (SCs) are …

Detection and activity profiling of synthetic cannabinoids and their metabolites with a newly developed bioassay

A Cannaert, J Storme, F Franz, V Auwärter… - Analytical …, 2016 - ACS Publications
Synthetic cannabinoids (SCs) are the largest group of compounds currently monitored in
Europe by the EU Early Warning System on new psychoactive substances. Emerging …

Baths salts, spice, and related designer drugs: the science behind the headlines

MH Baumann, E Solis, LR Watterson… - Journal of …, 2014 - Soc Neuroscience
The abuse of synthetic psychoactive substances known as “designer drugs,” or “new
psychoactive substances”(NPS), is increasing at an alarming rate. NPS are purchased as …

Moving around the molecule: relationship between chemical structure and in vivo activity of synthetic cannabinoids

JL Wiley, JA Marusich, JW Huffman - Life sciences, 2014 - Elsevier
Originally synthesized for research purposes, indole-and pyrrole-derived synthetic
cannabinoids are the most common psychoactive compounds contained in abused products …

Pharmacological and toxicological effects of synthetic cannabinoids and their metabolites

S Tai, WE Fantegrossi - … of New Psychoactive Substances (NPS) The …, 2017 - Springer
Commercial preparations containing synthetic cannabinoids (SCBs) are rapidly emerging as
drugs of abuse. Although often assumed to be “safe” and “legal” alternatives to cannabis …

Synthetic pot: not your grandfather's marijuana

BM Ford, S Tai, WE Fantegrossi, PL Prather - Trends in pharmacological …, 2017 - cell.com
In the early 2000s in Europe and shortly thereafter in the USA, it was reported that
'legal'forms of marijuana were being sold under the name K2 and/or Spice. Active …