Mitochondria are essential organelles with numerous functions in cellular metabolism and
homeostasis. Most of the> 1,000 different mitochondrial proteins are synthesized as …

Mitochondria contain∼ 1,000 different proteins, most of which are imported from the cytosol.
Two import pathways that direct proteins into the mitochondrial inner membrane and matrix …

Most mitochondrial proteins are synthesized on cytosolic ribosomes and must be imported
across one or both mitochondrial membranes. There is an amazingly versatile set of …

The translocase of the outer mitochondrial membrane (TOM) complex is the main entry gate
for mitochondrial precursor proteins synthesized on cytosolic ribosomes. Here we report the …

Most mitochondrial proteins are encoded in the nucleus. They are synthesized as precursor
forms in the cytosol and must be imported into mitochondria with the help of different protein …

Recent research has provided an abundance of new information on membrane
biochemistry. Now more than ever, it is essential to update our current understanding of …

The mitochondrion is arguably the most complex organelle in the budding yeast cell
cytoplasm. It is essential for viability as well as respiratory growth. Its innermost aqueous …

Adrenal gonadal, placental and brain mitochondria contain several steroidogenic enzymes,
notably the cholesterol side chain cleavage enzyme, P450scc, which is the enzymatic rate …

Mitochondrial fidelity is a key determinant of longevity and was found to be perturbed in a
multitude of disease contexts ranging from neurodegeneration to heart failure. Tight …

The biogenesis of mitochondria requires the import of a large number of proteins from the
cytosol [1, 2]. Although numerous studies have defined the proteinaceous machineries that …