Lipoarabinomannan and related glycoconjugates: structure, biogenesis and role in Mycobacterium tuberculosis physiology and host–pathogen interaction

AK Mishra, NN Driessen, BJ Appelmelk… - FEMS microbiology …, 2011 - academic.oup.com
Approximately one third of the world's population is infected with Mycobacterium
tuberculosis, the causative agent of tuberculosis. This bacterium has an unusual lipid-rich …

The glycosyltransferases of Mycobacterium tuberculosis—roles in the synthesis of arabinogalactan, lipoarabinomannan, and other glycoconjugates

S Berg, D Kaur, M Jackson, PJ Brennan - Glycobiology, 2007 - academic.oup.com
Several human pathogens are to be found within the bacterial genus Mycobacterium,
notably Mycobacterium tuberculosis, the causative agent of tuberculosis, one of the most …

Mycobacterial outer membrane is a lipid bilayer and the inner membrane is unusually rich in diacyl phosphatidylinositol dimannosides

R Bansal-Mutalik, H Nikaido - Proceedings of the National …, 2014 - National Acad Sciences
Mycobacterium species, including the human pathogen Mycobacterium tuberculosis, are
unique among Gram-positive bacteria in producing a complex cell wall that contains …

Characterization of inositol lipid metabolism in gut-associated Bacteroidetes

SL Heaver, HH Le, P Tang, A Baslé… - Nature …, 2022 - nature.com
Inositol lipids are ubiquitous in eukaryotes and have finely tuned roles in cellular signalling
and membrane homoeostasis. In Bacteria, however, inositol lipid production is relatively …

Plant myo-inositol transport influences bacterial colonization phenotypes

BS O'Banion, P Jones, AA Demetros, BR Kelley… - Current Biology, 2023 - cell.com
Plant microbiomes are assembled and modified through a complex milieu of biotic and
abiotic factors. Despite dynamic and fluctuating contributing variables, specific host …

Bacterial immunostat: Mycobacterium tuberculosis lipids and their role in the host immune response

A Queiroz, LW Riley - Revista da Sociedade Brasileira de Medicina …, 2017 - SciELO Brasil
The lipid-rich cell wall of Mycobacterium tuberculosis is a dynamic structure that is involved
in the regulation of the transport of nutrients, toxic host-cell effector molecules, and anti …

Structure of mycobacterial respiratory complex I

Y Liang, A Plourde, SA Bueler, J Liu… - Proceedings of the …, 2023 - National Acad Sciences
Oxidative phosphorylation, the combined activity of the electron transport chain (ETC) and
adenosine triphosphate synthase, has emerged as a valuable target for the treatment of …

PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of phosphatidylinositol mannoside in mycobacteria

YS Morita, CBC Sena, RF Waller, K Kurokawa… - Journal of Biological …, 2006 - ASBMB
Phosphatidylinositol mannosides (PIMs) are a major class of glycolipids in all mycobacteria.
AcPIM2, a dimannosyl PIM, is both an end product and a precursor for polar PIMs, such as …

C-type lectin receptor DCAR recognizes mycobacterial phosphatidyl-inositol mannosides to promote a Th1 response during infection

K Toyonaga, S Torigoe, Y Motomura, T Kamichi… - Immunity, 2016 - cell.com
Phosphatidyl-inositol mannosides (PIM) are glycolipids unique to mycobacteria and other
related bacteria that stimulate host immune responses and are implicated in mycobacteria …

Molecular basis of phosphatidyl-myo-inositol mannoside biosynthesis and regulation in mycobacteria

ME Guerin, J Korduláková, PM Alzari… - Journal of Biological …, 2010 - ASBMB
Phosphatidyl-myo-inositol mannosides (PIMs) are unique glycolipids found in abundant
quantities in the inner and outer membranes of the cell envelope of all Mycobacterium …