[HTML][HTML] Long COVID or post-acute sequelae of COVID-19 (PASC): an overview of biological factors that may contribute to persistent symptoms
AD Proal, MB VanElzakker - Frontiers in microbiology, 2021 - frontiersin.org
The novel virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused
a pandemic of coronavirus disease 2019 (COVID-19). Across the globe, a subset of patients …
a pandemic of coronavirus disease 2019 (COVID-19). Across the globe, a subset of patients …
Intranasal COVID-19 vaccines: From bench to bed
A Alu, L Chen, H Lei, Y Wei, X Tian, X Wei - EBioMedicine, 2022 - thelancet.com
Currently licensed COVID-19 vaccines are all designed for intramuscular (IM) immunization.
However, vaccination today failed to prevent the virus infection through the upper respiratory …
However, vaccination today failed to prevent the virus infection through the upper respiratory …
[HTML][HTML] Detection of viral infections by innate immunity
Pattern recognition receptors (PRRs) and inflammasomes are a key part of the anti-viral
innate immune system as they detect conserved viral pathogen-associated molecular …
innate immune system as they detect conserved viral pathogen-associated molecular …
Pseudomonas aeruginosa: Infections, Animal Modeling, and Therapeutics
SJ Wood, TM Kuzel, SH Shafikhani - Cells, 2023 - mdpi.com
Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which
causes many severe acute and chronic infections with high morbidity, and mortality rates as …
causes many severe acute and chronic infections with high morbidity, and mortality rates as …
[HTML][HTML] SARS-CoV-2 suppresses IFNβ production mediated by NSP1, 5, 6, 15, ORF6 and ORF7b but does not suppress the effects of added interferon
M Shemesh, TE Aktepe, JM Deerain, JL McAuley… - PLoS …, 2021 - journals.plos.org
Type I Interferons (IFN-Is) are a family of cytokines which play a major role in inhibiting viral
infection. Resultantly, many viruses have evolved mechanisms in which to evade the IFN-I …
infection. Resultantly, many viruses have evolved mechanisms in which to evade the IFN-I …
Lipid nanoparticle systems for enabling gene therapies
PR Cullis, MJ Hope - Molecular Therapy, 2017 - cell.com
Genetic drugs such as small interfering RNA (siRNA), mRNA, or plasmid DNA provide
potential gene therapies to treat most diseases by silencing pathological genes, expressing …
potential gene therapies to treat most diseases by silencing pathological genes, expressing …
Exploration of nanozymes in viral diagnosis and therapy
Nanozymes are nanomaterials with similar catalytic activities to natural enzymes. Compared
with natural enzymes, they have numerous advantages, including higher physiochemical …
with natural enzymes, they have numerous advantages, including higher physiochemical …
Human coronaviruses: a review of virus–host interactions
Human coronaviruses (HCoVs) are known respiratory pathogens associated with a range of
respiratory outcomes. In the past 14 years, the onset of severe acute respiratory syndrome …
respiratory outcomes. In the past 14 years, the onset of severe acute respiratory syndrome …
A scoping review of the pathophysiology of COVID-19
COVID-19 is a highly heterogeneous and complex medical disorder; indeed, severe COVID-
19 is probably amongst the most complex of medical conditions known to medical science …
19 is probably amongst the most complex of medical conditions known to medical science …
[HTML][HTML] The central role of the nasal microenvironment in the transmission, modulation, and clinical progression of SARS-CoV-2 infection
The novel coronavirus SARS-CoV-2 enters into the human body mainly through the ACE2+
TMPRSS2+ nasal epithelial cells. The initial host response to this pathogen occurs in a …
TMPRSS2+ nasal epithelial cells. The initial host response to this pathogen occurs in a …