The roles of choline and of choline-containing phospholipids (CCPLs) on the maintenance
and progress of neurovascular unit (NVU) integrity are analyzed. NVU is composed of …

This review is based on the previous one published in 2010–Secades JJ. Citicoline:
pharmacological and clinical review, 2010 update. Rev Neurol 2011; 52 (Suppl 2): S1-62 …

Identifying the health benefits of phytochemicals is an essential step in drug and functional
food development. While many in vitro screening methods have been developed to identify …

Choline participates in several relevant neurochemical processes. It is the precursor and
metabolite of acetylcholine (ACh), plays a role in single-carbon metabolism and is an …

Cholinergic precursors have represented the first approach to counter cognitive impairment
occurring in adultonset dementia disorders. These compounds were early leaved because …

Background Numerous magnetic resonance spectroscopy (MRS) studies have reported
metabolic abnormalities in the brains of patients with depression, although inconsistent …

Arterial hypertension is the main risk factor for stroke and plays a role in the development of
vascular cognitive impairment (VCI) and vascular dementia (VaD). An association between …

In this study, three popularly consumed salmonids, king salmon (Oncorhynchus
tshawytscha), Atlantic salmon (Salmo salar), and rainbow trout (Oncorhynchus mykiss), were …

Background Recent research on animal models of ischemic stroke supports the idea that
pharmacological treatment potentially enhancing intrinsic brain plasticity could modulate …

Vascular cognitive impairment is a process which is more frequent in patients with
cardiovascular risk factors. The etiology of this kind of impairment could be related to …