Hepatitis A virus infection
Hepatitis A is a vaccine-preventable infection caused by the hepatitis A virus (HAV). Over
150 million new infections of hepatitis A occur annually. HAV causes an acute inflammatory …
150 million new infections of hepatitis A occur annually. HAV causes an acute inflammatory …
Diagnosis of hepatitis A virus infection: a molecular approach
OV Nainan, G Xia, G Vaughan… - Clinical microbiology …, 2006 - Am Soc Microbiol
Current serologic tests provide the foundation for diagnosis of hepatitis A and hepatitis A
virus (HAV) infection. Recent advances in methods to identify and characterize nucleic acid …
virus (HAV) infection. Recent advances in methods to identify and characterize nucleic acid …
Reduction of the rate of poliovirus protein synthesis through large-scale codon deoptimization causes attenuation of viral virulence by lowering specific infectivity
Exploring the utility of de novo gene synthesis with the aim of designing stably attenuated
polioviruses (PV), we followed two strategies to construct PV variants containing synthetic …
polioviruses (PV), we followed two strategies to construct PV variants containing synthetic …
Evolution of codon usage in Zika virus genomes is host and vector specific
AM Butt, I Nasrullah, R Qamar… - Emerging microbes & …, 2016 - Taylor & Francis
The codon usage patterns of viruses reflect the evolutionary changes that allow them to
optimize their survival and adapt their fitness to the external environment and, most …
optimize their survival and adapt their fitness to the external environment and, most …
Codon usage bias and the evolution of influenza A viruses. Codon Usage Biases of Influenza Virus
Background The influenza A virus is an important infectious cause of morbidity and mortality
in humans and was responsible for 3 pandemics in the 20 th century. As the replication of …
in humans and was responsible for 3 pandemics in the 20 th century. As the replication of …
Genome-wide analysis of codon usage and influencing factors in chikungunya viruses
Chikungunya virus (CHIKV) is an arthropod-borne virus of the family Togaviridae that is
transmitted to humans by Aedes spp. mosquitoes. Its genome comprises a 12 kb single …
transmitted to humans by Aedes spp. mosquitoes. Its genome comprises a 12 kb single …
Modulation of poliovirus replicative fitness in HeLa cells by deoptimization of synonymous codon usage in the capsid region
CC Burns, J Shaw, R Campagnoli, J Jorba… - Journal of …, 2006 - Am Soc Microbiol
We replaced degenerate codons for nine amino acids within the capsid region of the Sabin
type 2 oral poliovirus vaccine strain with corresponding nonpreferred synonymous codons …
type 2 oral poliovirus vaccine strain with corresponding nonpreferred synonymous codons …
Hepatitis A virus: host interactions, molecular epidemiology and evolution
Infection with hepatitis A virus (HAV) is the commonest viral cause of liver disease and
presents an important public health problem worldwide. Several unique HAV properties and …
presents an important public health problem worldwide. Several unique HAV properties and …
Recombination and selection in the evolution of picornaviruses and other mammalian positive-stranded RNA viruses
P Simmonds - Journal of virology, 2006 - Am Soc Microbiol
Picornaviridae are a large virus family causing widespread, often pathogenic infections in
humans and other mammals. Picornaviruses are genetically and antigenically highly …
humans and other mammals. Picornaviruses are genetically and antigenically highly …
Genetic variability of hepatitis A virus
M Costa-Mattioli, AD Napoli, V Ferre… - Journal of General …, 2003 - microbiologyresearch.org
Knowledge of the molecular biology of hepatitis A virus (HAV) has increased exponentially
since its identification. HAV exploits all known mechanisms of genetic variation to ensure …
since its identification. HAV exploits all known mechanisms of genetic variation to ensure …