Modulating conjunctival wound healing has the potential to improve outcomes after
glaucoma filtration surgery and for several ocular disorders, including ocular cicatrial …

Huntington's disease (HD) is a fatal neurodegenerative disorder caused by the presence of
an abnormally expanded polyglutamine domain in the N-terminus of huntingtin. We …

Mesenchymal cell (MC) condensation or the aggregation of MCs precedes chondrocyte
differentiation and is required for subsequent cartilage formation during endochondral …

The cornea is particularly suited to gene therapy. The cornea is readily accessible, normally
transparent, and is somewhat sequestrated from the general circulation and the systemic …

The complex mechanisms by which transforming growth factor β (TGFβ) regulate re-
epithelialisation following injury of stratified epithelia are not fully understood. TGFβ signals …

Adipocyte differentiation is a key process implicated in the pathogenesis of obesity and
insulin resistance. Its regulation is triggered by a cascade of transcription factors, including …

Tendon injuries can occur in athletes and workers whose tasks involve repetitive, high‐force
hand activities, but the early pathophysiologic processes of tendinopathy are not well …

Connective tissue growth factor (CCN2) is a major pro-fibrotic factor that frequently acts
downstream of transforming growth factor beta (TGF-β)-mediated fibrogenic pathways. Much …

Connective Tissue Growth Factor (CTGF) and Transforming growth factor-β1 (TGF-β1) are
key growth factors in regulating corneal scarring. Although CTGF was induced by TGF-β1 …

Local invasion and distant metastasis are difficult problems for surgical intervention and
treatment in gastric cancer. Connective tissue growth factor (CTGF/CCN2) was considered …