Obesity in IBD: epidemiology, pathogenesis, disease course and treatment outcomes

S Singh, PS Dulai, A Zarrinpar… - Nature reviews …, 2017 - nature.com
Incidence of IBD is rising in parallel with overweight and obesity. Contrary to conventional
belief, about 15–40% of patients with IBD are obese, which might contribute to the …

Obesity as a surgical risk factor

M Ri, S Aikou, Y Seto - Annals of gastroenterological surgery, 2018 - Wiley Online Library
In recent years, both the actual number of overweight/obese individuals and their proportion
of the population have steadily been rising worldwide and obesity‐related diseases have …

Obesity, diabetes and the risk of colorectal adenoma and cancer

G Soltani, A Poursheikhani, M Yassi… - BMC endocrine …, 2019 - Springer
Background Colorectal cancer (CRC) is the fourth most commonly diagnosed
gastrointestinal (GI) malignancy and the third leading cause of cancer-related death …

The obese colorectal surgery patient: surgical site infection and outcomes

TS Wahl, FC Patel, LE Goss, DI Chu… - Diseases of the Colon …, 2018 - journals.lww.com
BACKGROUND: Obese patients undergoing colorectal surgery are at increased risk for
adverse outcomes. It remains unclear whether these risks can be further defined with more …

The mechanisms linking obesity to colon cancer: An overview

A Tarasiuk, P Mosińska, J Fichna - Obesity research & clinical practice, 2018 - Elsevier
Obesity, characterised as a chronic low-grade inflammation is a crucial risk factor for colon
cancer. The expansion of the adipose tissue is related to elevated triglyceride and low …

Impact of excess body weight on postsurgical complications

L Plassmeier, MK Hankir, F Seyfried - Visceral medicine, 2021 - karger.com
Background: Obesity is considered a risk factor for postoperative complications as it can limit
exposure to the operation field, thereby significantly prolonging surgery time. Obesity …

The effect of increasing body mass index on laparoscopic surgery for colon and rectal cancer

S Bell, JC Kong, R Wale, M Staples, K Oliva… - Colorectal …, 2018 - Wiley Online Library
Aim Obesity is common in Western countries and its prevalence is increasing. Colorectal
cancer is common, and surgery for colorectal cancer is technically more challenging in …

Obesity, cancer, and response to immune checkpoint inhibitors: Could the gut microbiota be the mechanistic link?

M Delaye, A Rousseau, L Mailly-Giacchetti… - Pharmacology & …, 2023 - Elsevier
Immune checkpoint inhibitors (ICI) have deeply changed the therapeutic management of a
broad spectrum of solid tumors. Recent observations showed that obese patients receiving …

An update on the pivotal roles of probiotics, their components, and metabolites in preventing colon cancer

X Deng, J Yang, Y Zhang, X Chen, C Wang, H Suo… - Foods, 2023 - mdpi.com
Diet, lifestyle, and gut microbiota composition are key risk factors for the progression of colon
cancer. Probiotics are living microorganisms that can offer health benefits to the parasitifer …

[HTML][HTML] Rising incidence of colorectal cancer in young adults corresponds with increasing surgical resections in obese patients

H Hussan, A Patel, M Le Roux… - Clinical and …, 2020 - journals.lww.com
OBJECTIVES: Strong evidence links obesity to esophageal cancer (EC), gastric cancer
(GC), colorectal cancer (CRC), and pancreatic cancer (PC). However, national-level studies …