Impact of stress on epilepsy: focus on neuroinflammation—a mini review

C Espinosa-Garcia, H Zeleke, A Rojas - International journal of molecular …, 2021 - mdpi.com
Epilepsy, one of the most common neurological disorders worldwide, is characterized by
recurrent seizures and subsequent brain damage. Despite strong evidence supporting a …

Biologically Active 2-Oxazolidinone Derivatives Beyond Antibacterial Activities

L Yuan, R Sheng, M Guan, Y Wang… - Current Medicinal …, 2023 - ingentaconnect.com
2-Oxazolidinone is well known as a pharmacophore for antibacterial agents represented by
two marketed medicines, Linezolid and Tedizolid. On the other hand, there are growing …

Non–cell autonomous epileptogenesis in focal cortical dysplasia

HY Koh, J Jang, SH Ju, R Kim, GB Cho… - Annals of …, 2021 - Wiley Online Library
Objective Low‐level somatic mosaicism in the brain has been shown to be a major genetic
cause of intractable focal epilepsy. However, how a relatively few mutation‐carrying neurons …

Technological Vanguard: the outstanding performance of the LTY-CNN model for the early prediction of epileptic seizures

Y Yang, T Luan, Z Yu, M Zhang, F Li, X Chen… - Journal of Translational …, 2024 - Springer
Background: Epilepsy is a common neurological disorder that affects approximately 60
million people worldwide. Characterized by unpredictable neural electrical activity …

Translocation of high mobility group box 1 from the nucleus to the cytoplasm in depressed patients with epilepsy

XL Li, S Wang, CY Tang, HW Ma, ZZ Cheng… - ASN …, 2022 - journals.sagepub.com
Depression is a common psychiatric comorbidity in patients with epilepsy, especially those
with temporal lobe epilepsy (TLE). The aim of this study was to assess changes in high …

A Novel Simple Gold Nanoparticles Pencil Electrode for Sensitive Voltametric Determination of Antiepileptic Drug Perampanel

AA Alfi, AAA Sari, ISS Alatawi, A Alharbi… - Journal of The …, 2024 - iopscience.iop.org
The construction and electroanalytical performance of a novel low-cost graphite pencil
sensor enriched with electrodeposited gold nanoparticles (AuNPs/PE) was for sensitive …

Identification of degradation products of brivaracetam using liquid chromatography quadrupole time‐of‐flight tandem mass spectrometry: Degradation pathway …

K Xu, M Ning, W Li, H Dong, Y Lu… - … in Mass Spectrometry, 2024 - Wiley Online Library
Rationale Pyrrolidone‐based drugs find widespread use in treating conditions such as
epilepsy and Alzheimer's disease, and in various other medical applications. Brivaracetam …

Shaping the future of European epilepsy research: Final meeting report from EPICLUSTER

DC Henshall, A Arzimanoglou, S Dedeurwaerdere… - Epilepsy Research, 2023 - Elsevier
Collaboration is essential to the conduct of basic, applied and clinical research and its
translation into the technologies and treatments urgently needed to improve the lives of …

The 2021 epilepsy research benchmarks—respecting core principles, reflecting evolving community priorities

ED Marsh, V Whittemore, M Leenders… - Epilepsy …, 2021 - journals.sagepub.com
Through a process that began formally in 2000, scientists, healthcare providers, and patient
advocates from across the country convened with representatives of governmental and …

Simple and Rapid LC-MS/MS Method for Determination of Perampanel in Human Plasma and Application to Bioequivalence Study

P Gao, Q Zou - Current Pharmaceutical Analysis, 2022 - ingentaconnect.com
Background: Perampanel (PER) is a third-generation antiepileptic drug (AED). Several
methods have been developed for the quantification of perampanel in plasma. The …