Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have been
recognized, among the large number of non-viral vectors for gene transfection, as an …

Solid lipid nanoparticles (SLNs) have been proposed in the 1990s as appropriate drug
delivery systems, and ever since they have been applied in a wide variety of cosmetic and …

Liver cancer is a leading cause of cancer deaths worldwide. The combination therapy of
cytotoxic and chemosensitizing agents loaded in nanoparticles has been highlighted as an …

Background Cervical cancer is a major world health problem for women. Currently, cancer
research focuses on improving therapy for cervical cancer using various treatment options …

Most of the active pharmaceutical ingredients are often prone to display low bioavailability,
biological degradation and inadvertent intrinsic side effects. To circumvent such obstacles …

Purpose Cationic solid lipid nanoparticles (SLN) have established themselves during the
past decades. They can efficiently bind DNA directly via ionic interaction and mediate gene …

The accurate detection of Protamine and Trypsin, two biomolecules with significant clinical
and biological relevance, presents a substantial challenge because of their structural …

The introduction of therapeutic genes in target tissues is considered as a novel tool for the
treatment of several diseases. We have developed nanoparticles consisting on SLNs …

The lipids are a large group of organic compounds that has a fundamental role in life on
Earth. Whether they act as the energy storage in our bodies or as the building blocks of the …

Purpose Cisplatin plus gemcitabine (GEM) is a standard regimen for the first-line treatment
of advanced non-small cell lung cancer. The aim of this study was to prepare biocompatible …