There is rapidly expanding interest in interventions to slow myopia progression in children
and teenagers, with the intent of reducing risk of myopia-associated complications later in …

Clinical trials are time consuming, expensive, and often burdensome on patients. Clinical
trials can fail for many reasons. This survey reviews many of these reasons and offers …

Objectives To identify and appraise the most recent studies reporting dental implant survival
in adults (≥ 18 years) using contemporary implant systems (solid screw, roughened …

Background The pharmaceutical industry is in the midst of a productivity crisis and rates of
translation from bench to bedside are dismal. Patients are being let down by the current …

Toll‐like receptors (TLRs) are germline‐encoded receptors that are central to innate and
adaptive immune responses. Owing to their vital role in inflammation, TLRs are rational …

Chronic diseases, including metabolic diseases, have become a worldwide public health
issue. Research regarding the use of bioactive peptides or protein hydrolysates derived from …

We wish to answer this question: If you observe a 'significant'p-value after doing a single
unbiased experiment, what is the probability that your result is a false positive? The weak …

Advances in the understanding of disease biology, drug development, and supportive care
have led to improved outcomes in multiple myeloma. Given that these improvements have …

Background Neonatal research evaluates many different outcomes using multiple
measures. This can prevent synthesis of trial results in meta-analyses, and selected …

An increasing number of young and previously fit and healthy people who did not require
hospitalisation continue to have symptoms months after mild cases of COVID-19 …