According to the first publication in 1993 by Rauscher et al.[Nature 1993; 365: 611], the
Mozart effect implies the enhancement of reasoning skills solving spatial problems in normal …

Cenobamate (CNB),([(R)-1-(2-chlorophenyl)-2-(2H-tetrazol-2-yl) ethyl], is a novel tetrazole
alkyl carbamate derivative. In November 2019, the Food and Drug Administration approved …

New, more effective pharmacologic treatments for epilepsy are needed, as a substantial
portion of patients (> 30%) are refractory to currently available anti-epileptic drugs …

Cenobamate, which is a voltage-gated sodium channel (VGSC) blocker, finds its full
application in several anti-epileptic medications. This manuscript tries to look at the structure …

Epilepsy is a common, disabling illness that is refractory to medical treatment in
approximately one-third of patients, particularly among those with mesial temporal lobe …

Accumulating evidences indicate that thiamine plays a vital role in the nervous system.
However, questions exist as to how it causes epilepsy, neuronal damage, and antiepileptic …

In a previous study, we uncovered the anticonvulsant properties of turmeric oil and its
sesquiterpenoids (ar-turmerone, α-, β-turmerone and α-atlantone) in both zebrafish and …

Epilepsies represent one of the most common neurological diseases worldwide. They are
characterized by recurrent spontaneous seizures with severe impact on a patient's life. An …

In the present study, we have synthesized a series of fifteen nipecotic acid 1, 3, 4-oxadiazole
based hybrids with significant (60–78%) yields. All the compounds were characterized by …

The duration and, age of dementia have been linked to a higher risk of seizures. The exact
mechanism that drives epileptogenesis in impaired mitophagy and autophagy linked …