Helicobacter pylori is a gastric pathogen that colonizes approximately 50% of the world's
population. Infection with H. pylori causes chronic inflammation and significantly increases …

Helicobacter pylori colonizes the majority of persons worldwide, and the ensuing gastric
inflammatory response is the strongest singular risk factor for peptic ulceration and gastric …

The prognosis of advanced gastric cancer remains extremely poor despite the use of
standard therapies such as chemotherapy and biological agents. Blocking immune …

Helicobacter pylori is a gram-negative bacterium that persistently colonizes more than half of
the global human population. In order to successfully colonize the human stomach, H. pylori …

Many common cancers develop as a consequence of years of chronic inflammation.
Increasing evidence indicates that the inflammation may result from persistent mucosal or …

The intestinal epithelium is a critical interface between the organism and its environment.
The cell polarity and structural properties of the enterocytes, limiting the amount of antigen …

To elucidate the pathogenesis of Helicobacter pylori-associated gastritis, we studied
immune responses of C57BL/6J wild-type (WT), SCID, and gene deficient (IFN-γ−/− and IL …

Helicobacter pylori infects the stomach of half of the human population worldwide and
causes chronic active gastritis, which can lead to peptic ulcer disease, gastric …

Background & Aims: It is not clear how Helicobacter pylori, an apparently extracellular
pathogen colonizing the luminal side of the gastric epithelium, invariably causes an immune …

The prevalence of gastric cancer is associated with several factors including geographical
location, diet, and genetic background of the host. However, it is evident that infection with …