Decoding the cancer stem cell hypothesis in glioblastoma

JS Hale, M Sinyuk, JN Rich, JD Lathia - CNS oncology, 2013 - Taylor & Francis
Our understanding of the complexity of nervous system cancers has been enhanced through
the incorporation of cellular heterogeneity into tumor models, with cellular subsets …

Differences in enhancer activity in mouse and zebrafish reporter assays are often associated with changes in gene expression

A Ariza-Cosano, A Visel, LA Pennacchio, HB Fraser… - BMC genomics, 2012 - Springer
Background Phenotypic evolution in animals is thought to be driven in large part by
differences in gene expression patterns, which can result from sequence changes in cis …

Expression of mammalian ASH1 and ASH4 in Drosophila reveals opposing functional roles in neurogenesis

B Sun, J Tu, Q Liang, X Cheng, X Fan, Y Li… - Gene, 2019 - Elsevier
To investigate whether the members of the mammalian Achaete-Scute Complex homologue
(ASH) gene family have evolved functional differences, we used the patterning of bristles as …

Characterization of an enhancer upstream of msx3 and its role in development of the neural tube of embryonic and larval zebrafish

S Keil - 2023 - ruor.uottawa.ca
The vertebrate nervous system arises during embryogenesis from an epithelial sheet of cells
called the neural plate that subsequently folds to become a rod of cells called the neural …

[图书][B] Functional evaluation of noncoding regulatory control provides novel insights into their constraint, distribution, and overlapping functions

D McGaughey - 2010 - search.proquest.com
Functional non-coding DNA has important roles in the temporal, spatial, and quantitative
expression of genes in development, disease, homeostasis, and inter-species variation. One …