Transfusion Medicine is a dynamically evolving field. Recent high-quality research has
reshaped the paradigms guiding blood transfusion. As increasing evidence supports the …

Introduction Hemorrhage is a leading cause of death among trauma patients, and is the
most common cause of preventable death after trauma. Since the advent of blood …

Objective: The aim of this study was to identify a mortality benefit with the use of whole blood
(WB) as part of the resuscitation of bleeding trauma patients. Background: Blood component …

PURPOSE Following US military implementation of a cold-stored whole blood program,
several US trauma centers have begun incorporating uncrossmatched, group O cold-stored …

BACKGROUND There is a resurgence in the use of low‐titer group O whole blood (LTOWB)
for hemorrhagic shock. We hypothesized the use of LTOWB compared to component …

The transmembrane P-glycoprotein (P-gp) pumps that efflux drugs are a major mechanism
of cancer drug resistance. They are also important in protecting normal tissue cells from …

METHODS We performed a single-center, prospective, cluster randomized, prehospital
through in-hospital whole blood pilot trial for injured air medical patients. We compared …

METHODS We analyzed the (2015–2016) Trauma Quality Improvement Program. We
included adult (age,≥ 18 years) trauma patients presenting with hemorrhagic shock and …

Background Death from uncontrolled hemorrhage occurs rapidly, particularly among combat
casualties. The US military has used warm fresh whole blood during combat operations …

Abstract Background Low‐titer Group O Whole Blood (LTOWB) is used with increasing
frequency in adult and pediatric trauma and massive bleeding transfusion protocols. There …