[HTML][HTML] Increasing number of long-lived ancestors marks a decade of healthspan extension and healthier metabolomics profiles

N van den Berg, M Rodríguez-Girondo… - Nature …, 2023 - nature.com
Globally, the lifespan of populations increases but the healthspan is lagging behind.
Previous research showed that survival into extreme ages (longevity) clusters in families as …

[PDF][PDF] Born close to death. Region, Roman Catholicism and infant mortality in the Netherlands, 1875-1899

NJM van den Boomen - 2021 - repository.ubn.ru.nl
For 2019, the World Health Organization predicted that vaccine hesitancy–the delayed
acceptance or outright refusal to use the available vaccination services–posed one of ten …

[HTML][HTML] Exploring familial factors in the migrant mortality advantage among domestic migrants in later life: Zeeland, the Netherlands, 1812–1962

RJ Mourits, P Puschmann - SSM-Population Health, 2023 - Elsevier
Many historical and contemporary studies have shown that migrants enjoy survival
advantages over non-migrants, even if they originate from higher mortality regimes and have …

Longevity Relatives Count score identifies heritable longevity carriers and suggests case improvement in genetic studies

N van den Berg, M Rodríguez‐Girondo… - Aging …, 2020 - Wiley Online Library
Loci associated with longevity are likely to harbor genes coding for key players of molecular
pathways involved in a lifelong decreased mortality and decreased/compressed morbidity …

Increasing number of long-lived ancestors associates with up to a decade of healthspan extension and a healthy metabolomic profile in mid-life

N van den Berg, M Rodríguez-Girondo, IK van Dijk… - bioRxiv, 2022 - biorxiv.org
Globally, the lifespan of populations increases but the healthspan is lagging behind.
Previous research showed that survival into extreme ages (longevity) clusters in families as …

The long-term consequences of parental death in childhood on mortality and the role of socioeconomic status: evidence from Sweden at the turn of the 20th century

E Debiasi, M Rosenbaum-Feldbrügge… - The History of the …, 2021 - Taylor & Francis
The death of a parent during childhood is a major traumatic event. While there is a good
understanding of the early-life effects of parental loss, the evidence regarding its impact on …

Developmental origins of exceptional health and survival: A four-generation family cohort study

MT Keys, DA Pedersen, PS Larsen, A Kulminski… - medRxiv, 2024 - medrxiv.org
Descendants of longevity-enriched sibships demonstrate a broad health and survival
advantage throughout the life course. However, little is known about manifestations during …

Intergenerational Transmission of Health and Life span: An Exploration of an Association Between Parental Age-at-Death and Disease Outcomes in Offspring

A Thalén - 2022 - diva-portal.org
Parental and offspring life spans are modestly associated and a transmission of disease risk
from parents to offspring has been proposed as a possible explanation. Using birth cohort …

[HTML][HTML] Improved selection of participants in genetic longevity studies: family scores revisited

M Rodríguez-Girondo, N van den Berg, MH Hof… - BMC Medical Research …, 2021 - Springer
Background Although human longevity tends to cluster within families, genetic studies on
longevity have had limited success in identifying longevity loci. One of the main causes of …

An exploration of the social factors and characteristics of Irish centenarians

A Fagan - 2023 - research.thea.ie
Globally, societies are amid a longevity revolution. By virtue of their longevous life,
centenarians, have been widely accepted as models for successful ageing. Numerous …