Agmatine: multifunctional arginine metabolite and magic bullet in clinical neuroscience?

G Laube, HG Bernstein - Biochemical Journal, 2017 - portlandpress.com
Agmatine, the decarboxylation product of arginine, was largely neglected as an important
player in mammalian metabolism until the mid-1990s, when it was re-discovered as an …

The pharmacological importance of agmatine in the brain

TI Uzbay - Neuroscience & Biobehavioral Reviews, 2012 - Elsevier
Agmatine is a polyamine that is produced via decarboxylation of l-arginine by the enzyme
arginine decarboxylase. It binds to various receptors and has been accepted as a novel …

Moringa oleifera supplemented diet modulates nootropic-related biomolecules in the brain of STZ-induced diabetic rats treated with acarbose

G Oboh, SI Oyeleye, OA Akintemi… - Metabolic brain disease, 2018 - Springer
There are strong correlations between diabetes mellitus and cognitive dysfunction. This
study sought to investigate the modulatory effects of Moringa oleifera leaf (ML) and seed …

Antioxidative effects of caffeine in a hyperoxia-based rat model of bronchopulmonary dysplasia

S Endesfelder, E Strauß, T Scheuer, T Schmitz… - Respiratory …, 2019 - Springer
Background While additional oxygen supply is often required for the survival of very
premature infants in intensive care, this also brings an increasing risk of progressive lung …

A novel in vitro metabolomics approach for neurotoxicity testing, proof of principle for methyl mercury chloride and caffeine

E Van Vliet, S Morath, C Eskes, J Linge, J Rappsilber… - Neurotoxicology, 2008 - Elsevier
There is a need for more efficient methods giving insight into the complex mechanisms of
neurotoxicity. Testing strategies including in vitro methods have been proposed to comply …

[HTML][HTML] Phyllanthus amarus Schumach. & Thonn. and Momordica charantia L extracts improve memory function, attenuate cholinergic and purinergic dysfunction, and …

SI Oyeleye, TA Olasehinde, OW Fasakin, G Oboh… - Phytomedicine Plus, 2022 - Elsevier
Background Phyllanthus amarus (PA) and Momordica charantia (MC) are common herbs
known for their various pharmacological importance. However, limited studies have been …

Long-term exposure of polychaetes to caffeine: biochemical alterations induced in Diopatra neapolitana and Arenicola marina

A Pires, Â Almeida, V Calisto, RJ Schneider… - Environmental …, 2016 - Elsevier
In the last decade studies have reported the presence of several pharmaceutical drugs in
aquatic environments worldwide and an increasing effort has been done to understand the …

[HTML][HTML] Effect of caffeine on oxidative stress during maximum incremental exercise

GJ Olcina, D Muñoz, R Timón… - Journal of sports …, 2006 - ncbi.nlm.nih.gov
Abstract Caffeine (1, 3, 7-trimethylxanthine) is an habitual substance present in a wide
variety of beverages and in chocolate-based foods and it is also used as adjuvant in some …

The arginase pathway in neonatal brain hypoxia-ischemia

J Krystofova, P Pathipati, J Russ, A Sheldon… - Developmental …, 2019 - karger.com
Brain damage after hypoxia-ischemia (HI) occurs in an age-dependent manner.
Neuroprotective strategies assumed to be effective in adults might have deleterious effects …

[HTML][HTML] Caffeine-supplemented diet modulates oxidative stress markers and improves locomotor behavior in the lobster cockroach Nauphoeta cinerea

CS da Silva, RCG de Lima, OO Elekofehinti… - Chemico-biological …, 2018 - Elsevier
The effects of caffeine supplementation is well documented in conventional animal models,
however, in the lobster cockroaches Nauphoeta cinerea, they have not been reported. Thus …