The Hsp70 family members play an essential role in cellular protein metabolism by acting as polypeptide-binding and release factors that interact with nonnative regions of proteins at …
Despite recent progress in our understanding of carotenogenesis in plants, the mechanisms that govern overall carotenoid accumulation remain largely unknown. The Orange (Or) gene …
GC Meacham, Z Lu, S King, E Sorscher… - The EMBO …, 1999 - embopress.org
The cystic fibrosis transmembrane conductance regulator (CFTR) is a chloride ion channel constructed from two membrane‐spanning domains (MSDs), two nucleotide‐binding …
JC Young - Biochemistry and cell biology, 2010 - cdnsciencepub.com
Molecular chaperones of the Hsp70 family have diverse functions in cells. They assist the folding of newly synthesized and stress-denatured proteins, as well as the import of proteins …
MK Greene, K Maskos… - Proceedings of the …, 1998 - National Acad Sciences
The Escherichia coli Hsp40 DnaJ and Hsp70 DnaK cooperate in the binding of proteins at intermediate stages of folding, assembly, and translocation across membranes. Binding of …
S Rüdiger, J Schneider‐Mergener, B Bukau - The EMBO journal, 2001 - embopress.org
The evolutionarily conserved DnaJ proteins are essential components of Hsp70 chaperone systems. The DnaJ homologue of Escherichia coli associates with chaperone substrates …
Y Yang, Y Qin, C Xie, F Zhao, J Zhao, D Liu… - The Plant …, 2010 - academic.oup.com
The plasma membrane H+-ATPase (PM H+-ATPase) plays an important role in the regulation of ion and metabolite transport and is involved in physiological processes that …
▪ Abstract The endoplasmic reticulum (ER) serves as a way-station during the biogenesis of nearly all secreted proteins, and associated with or housed within the ER are factors …
Environmental and occupational exposure to heavy metals such as cadmium, mercury and lead results in severe health hazards including prenatal and developmental defects. The …