IL-22 is a relatively new cytokine that is characterized by several unique biological
properties. In the intestines, the effect of IL-22 is restricted mainly to non-lymphoid cells such …

Chronic pancreatitis is a multifactorial, fibroinflammatory syndrome in which repetitive
episodes of pancreatic inflammation lead to extensive fibrotic tissue replacement, resulting …

Manipulations of morphological properties of nanobiomaterials have been demonstrated to
modulate the outcome of osteoimmunomodulation and eventually osteogenesis through …

This paper reviews the current status of our understanding of the epidemiology, diagnosis,
and management of the continuum of pancreatic diseases from acute and recurrent acute …

Chronic pancreatitis is characterized by progressive, irreversible morphologic and functional
changes that are most commonly attributed to environmental insults, particularly when there …

Activated pancreatic stellate cells (PSCs) are the main effector cells in the process of
fibrosis, a major pathological feature in pancreatic diseases that including chronic …

Inflammatory immune cells can modulate activation of hepatic stellate cells (HSCs) and
progression of liver fibrosis. Type 3 inflammation characterized by production of interleukin …

METHODS: Patients with clinical and imaging evidence of CP (n= 51) were prospectively
recruited and compared with twice the number of nonpancreatic disease controls matched …

Background Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of
cancer-associated mortality worldwide with an overall five-year survival rate less than 7 …

Objectives: Rare pathogenic variants in the SPINK1, PRSS1, CTRC, and CFTR genes have
been strongly associated with a risk of developing chronic pancreatitis (CP). However, their …