Translating eco-evolutionary biology into therapy to tackle antibiotic resistance
Antibiotic resistance is currently one of the most important public health problems. The
golden age of antibiotic discovery ended decades ago, and new approaches are urgently …
golden age of antibiotic discovery ended decades ago, and new approaches are urgently …
Revisiting antibiotic resistance: mechanistic foundations to evolutionary outlook
CM Hasan, D Dutta, ANT Nguyen - Antibiotics, 2021 - mdpi.com
Antibiotics are the pivotal pillar of contemporary healthcare and have contributed towards its
advancement over the decades. Antibiotic resistance emerged as a critical warning to public …
advancement over the decades. Antibiotic resistance emerged as a critical warning to public …
Fluoroquinolone Residues in the Environment Rapidly Induce Heritable Fluoroquinolone Resistance in Escherichia coli
Extensive antibiotic use increases the environmental presence of their residues and may
accelerate the development of antibiotic resistance, although this remains poorly understood …
accelerate the development of antibiotic resistance, although this remains poorly understood …
Compensatory evolution of Pseudomonas aeruginosa's slow growth phenotype suggests mechanisms of adaptation in cystic fibrosis
Long-term infection of the airways of cystic fibrosis patients with Pseudomonas aeruginosa
is often accompanied by a reduction in bacterial growth rate. This reduction has been …
is often accompanied by a reduction in bacterial growth rate. This reduction has been …
Multidrug resistance (MDR) and collateral sensitivity in bacteria, with special attention to genetic and evolutionary aspects and to the perspectives of antimicrobial …
Antibiotic poly-resistance (multidrug-, extreme-, and pan-drug resistance) is controlled by
adaptive evolution. Darwinian and Lamarckian interpretations of resistance evolution are …
adaptive evolution. Darwinian and Lamarckian interpretations of resistance evolution are …
Multi-step vs. single-step resistance evolution under different drugs, pharmacokinetics, and treatment regimens
The success of antimicrobial treatment is threatened by the evolution of drug resistance.
Population genetic models are an important tool in mitigating that threat. However, most …
Population genetic models are an important tool in mitigating that threat. However, most …
The roles of history, chance, and natural selection in the evolution of antibiotic resistance
History, chance, and selection are the fundamental factors that drive and constrain evolution.
We designed evolution experiments to disentangle and quantify effects of these forces on …
We designed evolution experiments to disentangle and quantify effects of these forces on …
Large-scale genomic analysis of antimicrobial resistance in the zoonotic pathogen Streptococcus suis
NF Hadjirin, EL Miller, GGR Murray, PLK Yen, HD Phuc… - BMC biology, 2021 - Springer
Background Antimicrobial resistance (AMR) is among the gravest threats to human health
and food security worldwide. The use of antimicrobials in livestock production can lead to …
and food security worldwide. The use of antimicrobials in livestock production can lead to …
[HTML][HTML] Comparative selective pressure potential of antibiotics in the environment
To guide both environmental and public health policy, it is important to assess the degree of
antibiotic resistance selection pressure under measured environmental concentrations …
antibiotic resistance selection pressure under measured environmental concentrations …
[HTML][HTML] Antioxidant and antimicrobial potentials of mycelial extracts of Hohenbuehelia myxotricha grown in different liquid culture media
In addition to their nutritional properties, mushrooms have emerged as a health supplement
because of their medicinal potential. Many studies have shown that mushrooms exhibit …
because of their medicinal potential. Many studies have shown that mushrooms exhibit …