[HTML][HTML] The ABC gene family in arthropods: comparative genomics and role in insecticide transport and resistance

W Dermauw, T Van Leeuwen - Insect biochemistry and molecular biology, 2014 - Elsevier
About a 100 years ago, the Drosophila white mutant marked the birth of Drosophila genetics.
The white gene turned out to encode the first well studied ABC transporter in arthropods …

Insect ATP-binding cassette (ABC) transporters: roles in xenobiotic detoxification and Bt insecticidal activity

C Wu, S Chakrabarty, M Jin, K Liu, Y Xiao - International journal of …, 2019 - mdpi.com
ATP-binding cassette (ABC) transporters, a large class of transmembrane proteins, are
widely found in organisms and play an important role in the transport of xenobiotics. Insect …

The role of eukaryotic and prokaryotic ABC transporter family in failure of chemotherapy

R El-Awady, E Saleh, A Hashim, N Soliman… - Frontiers in …, 2017 - frontiersin.org
Over the years chemotherapy failure has been a vital research topic as researchers have
been striving to discover reasons behind it. The extensive studies carried out on …

Mechanistic insights into chemical conditioning on transformation of dissolved organic matter and plant biostimulants production during sludge aerobic composting

Y Zhang, B Yang, S Peng, Z Zhang, S Cai, J Yu… - Water Research, 2024 - Elsevier
Inorganic coagulants (aluminum and iron salt) are widely used to improve sludge
dewaterability, resulting in numerous residues in dewatered sludge. Composting refers to …

Mosquitoes cloak their legs to resist insecticides

V Balabanidou, M Kefi, M Aivaliotis… - … of the Royal …, 2019 - royalsocietypublishing.org
Malaria incidence has halved since the year 2000, with 80% of the reduction attributable to
the use of insecticides. However, insecticide resistance is now widespread, is rapidly …

Transcriptomic meta-signatures identified in Anopheles gambiae populations reveal previously undetected insecticide resistance mechanisms

VA Ingham, S Wagstaff, H Ranson - Nature communications, 2018 - nature.com
Increasing insecticide resistance in malaria-transmitting vectors represents a public health
threat, but underlying mechanisms are poorly understood. Here, a data integration approach …

A burst of ABC genes in the genome of the polyphagous spider mite Tetranychus urticae

W Dermauw, EJ Osborne, RM Clark, M Grbić, L Tirry… - BMC genomics, 2013 - Springer
Abstract Background The ABC (ATP-binding cassette) gene superfamily is widespread
across all living species. The majority of ABC genes encode ABC transporters, which are …

Chitin is a necessary component to maintain the barrier function of the peritrophic matrix in the insect midgut

M Kelkenberg, J Odman-Naresh… - Insect Biochemistry and …, 2015 - Elsevier
In most insects, the peritrophic matrix (PM) partitions the midgut into different digestive
compartments, and functions as a protective barrier against abrasive particles and microbial …

A Systematic Study of RNAi Effects and dsRNA Stability in Tribolium castaneum and Acyrthosiphon pisum, Following Injection and Ingestion of Analogous dsRNAs

M Cao, JA Gatehouse, EC Fitches - International journal of molecular …, 2018 - mdpi.com
RNA interference (RNAi) effects in insects are highly variable and may be largely dependent
upon the stability of introduced double-stranded RNAs to digestion by nucleases. Here, we …

Down-regulation of a novel ABC transporter gene (Pxwhite) is associated with Cry1Ac resistance in the diamondback moth, Plutella xylostella (L.)

Z Guo, S Kang, X Zhu, J Xia, Q Wu, S Wang… - Insect biochemistry and …, 2015 - Elsevier
Biopesticides or transgenic crops based on Cry toxins from the soil bacterium Bacillus
thuringiensis (Bt) effectively control agricultural insect pests. The sustainable use of Bt …