Atrial fibrillation burden: a new outcome predictor and therapeutic target

N Becher, A Metzner, T Toennis, P Kirchhof… - European Heart …, 2024 - academic.oup.com
Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, is not a dichotomous
disease trait. Technological innovations enable long-term rhythm monitoring in many …

Innovative approaches to atrial fibrillation prediction: should polygenic scores and machine learning be implemented in clinical practice?

AM Petzl, G Jabbour, J Cadrin-Tourigny… - Europace, 2024 - academic.oup.com
Atrial fibrillation (AF) prediction and screening are of important clinical interest because of
the potential to prevent serious adverse events. Devices capable of detecting short episodes …

Atrial cardiomyopathy revisited—evolution of a concept: a clinical consensus statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart …

A Goette, D Corradi, D Dobrev, L Aguinaga… - Europace, 2024 - academic.oup.com
Aims The concept of “atrial cardiomyopathy”(AtCM) had been percolating through the
literature since its first mention in 1972. Since then, publications using the term were …

Apixaban vs aspirin in patients with cancer and cryptogenic stroke: a post hoc analysis of the ARCADIA randomized clinical trial

BB Navi, C Zhang, B Miller, M Cushman… - JAMA …, 2024 - jamanetwork.com
Importance Approximately 10% to 15% of ischemic strokes are associated with cancer;
cancer-associated stroke, particularly when cryptogenic, is associated with high rates of …

Anticoagulation in patients with device‐detected atrial fibrillation with and without a prior stroke or transient ischemic attack: the NOAH‐AFNET 6 trial

HC Diener, N Becher, S Sehner, T Toennis… - Journal of the …, 2024 - ahajournals.org
Background Short and rare episodes of atrial fibrillation (AF) are commonly detected using
implanted devices (device‐detected AF) in patients with prior stroke or transient ischemic …

Direct oral anticoagulants: quick primer on when to use and when to avoid

A Bejjani, B Bikdeli - Thrombosis and Haemostasis, 2024 - thieme-connect.com
Direct oral anticoagulants (DOACs) have transformed the landscape of antithrombotic
therapy in the past two decades. However, there is uncertainty about when they should or …

Longer and better lives for patients with atrial fibrillation: the 9th AFNET/EHRA consensus conference

D Linz, JG Andrade, E Arbelo, G Boriani… - Europace, 2024 - academic.oup.com
Aims Recent trial data demonstrate beneficial effects of active rhythm management in
patients with atrial fibrillation (AF) and support the concept that a low arrhythmia burden is …

Anticoagulation vs antiplatelets across subgroups of embolic stroke of undetermined source: a meta-analysis of randomized controlled trials

M Ghannam, AM Al-Qudah, QN Alshaer, R Kronmal… - Neurology, 2024 - neurology.org
Background and Objectives The term “embolic stroke of undetermined source”(ESUS)
encompasses a substantial but heterogeneous population of patients with ischemic stroke …

Embolic strokes of undetermined source: a clinical consensus statement of the ESC Council on Stroke, the European Association of Cardiovascular Imaging and the …

G Ntaios, H Baumgartner, W Doehner… - European Heart …, 2024 - academic.oup.com
One in six ischaemic stroke patients has an embolic stroke of undetermined source (ESUS),
defined as a stroke with unclear aetiology despite recommended diagnostic evaluation. The …

Risk of Intracranial Hemorrhage Associated With Direct Oral Anticoagulation vs Antiplatelet Therapy: A Systematic Review and Meta-Analysis

M Coyle, A Lynch, M Higgins, M Costello… - JAMA Network …, 2024 - jamanetwork.com
Importance For patients with atrial fibrillation, clinicians often prescribe antiplatelet therapy
rather than oral anticoagulation, which may be related to a concern that direct oral …