Interferon (IFN)-mediated antiviral responses are central to host defence against viral
infection. Despite the existence of at least 20 IFNs, there are only three known cell surface …

ABSTRACT Introduction: TANK-binding kinase 1 (TBK1) is vital for the induction of antiviral
innate immune responses. Both RNA and DNA viral infection induces TBK1 activation …

As a neurotropic virus, human Enterovirus 71 (EV71) infection causes hand-foot-and-mouth
disease (HFMD) and may develop severe neurological disorders in infants. Toll-like receptor …

Loop-mediated isothermal amplification (LAMP) is widely used in detection of pathogenic
microorganisms including SARS-CoV-2. However, the performance of LAMP assay needs …

ABSTRACT The 2019 coronavirus disease (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) highlighted significant gaps in our …

Enteroviruses infect gastrointestinal epithelium cells, cause multiple human diseases, and
present public health risks worldwide. However, the mechanisms underlying host immune …

Cancer progression is frequently caused by metastasis and leads to significantly increased
mortality. Cell derived extracellular vesicles, including exosomes, in the microenvironment …

Zika virus (ZIKV) infection to a pregnant woman can be vertically transmitted to the fetus via
the placenta leading to Congenital Zika syndrome. This is characterized by microcephaly …

Previous studies have shown that DEAD (Asp-Glu-Ala-Asp)-box RNA helicases play
important roles in viral infection, either as cytosolic sensors of pathogenic molecules or as …

Homocysteine-inducible endoplasmic reticulum protein (HERP) is an endoplasmic reticulum
(ER)-resident protein and important for the adaptation of cellular protein homeostasis by ER …