Therapeutic potential of certain terpenoids as anticancer agents: a scoping review

S Kamran, A Sinniah, MAM Abdulghani, MA Alshawsh - Cancers, 2022 - mdpi.com
Simple Summary Terpenoids are bioactive compounds with a variety of pharmacological
activities, including anticancer activity. This review paper aimed to focus on the anticancer …

Betulin and its derivatives as novel compounds with different pharmacological effects

S Amiri, S Dastghaib, M Ahmadi, P Mehrbod… - Biotechnology …, 2020 - Elsevier
Betulin (B) and Betulinic acid (BA) are natural pentacyclic lupane-structure triterpenoids
which possess a wide range of pharmacological activities. Recent evidence indicates that B …

Anti-inflammatory and anticancer properties of birch bark-derived betulin: recent developments

HS Tuli, K Sak, DS Gupta, G Kaur, D Aggarwal… - Plants, 2021 - mdpi.com
Birch tree bark-derived betulin has attracted scientific interest already for several centuries,
being one of the first natural products identified from plants. However, the cellular events …

Therapeutic potential of natural products in inflammation: Underlying molecular mechanisms, clinical outcomes, technological advances, and future perspectives

NA Gouda, SO Alshammari, MAS Abourehab… - …, 2023 - Springer
Chronic inflammation is a common underlying factor in many major diseases, including
heart disease, diabetes, cancer, and autoimmune disorders, and is responsible for up to …

Diversity, phytochemical and medicinal potential of the genus Ocimum L. (Lamiaceae)

EM Zahran, UR Abdelmohsen, HE Khalil… - Phytochemistry …, 2020 - Springer
Ocimum, commonly known as Tulsi, is a huge genus within family Lamiaceae, comprising
about 64 species of annual to perennial aromatic medicinal herbs with a long history of …

Pentacyclic triterpenoid phytochemicals with anticancer activity: Updated studies on mechanisms and targeted delivery

M Nistor, D Rugina, Z Diaconeasa, C Socaciu… - International Journal of …, 2023 - mdpi.com
Pentacyclic triterpenoids (TTs) represent a unique family of phytochemicals with interesting
properties and pharmacological effects, with some representatives, such as betulinic acid …

Betulin and its derivatives reduce inflammation and COX-2 activity in macrophages

W Szlasa, S Ślusarczyk, I Nawrot-Hadzik, R Abel… - Inflammation, 2023 - Springer
Betulin is a heavily studied natural compound for its use as an anticancer or pro-
regenerative agent. The structural similarity between betulin to steroids gives rise to the idea …

Antimicrobial potential of betulinic acid and investigation of the mechanism of action against nuclear and metabolic enzymes with molecular modeling

GCS Rodrigues, M dos Santos Maia, TA de Souza… - Pathogens, 2023 - mdpi.com
Natural products have important pharmacological activities. This study sought to investigate
the activity of the compound betulinic acid (BA) against different strains of bacteria and fungi …

Nanoencapsulated betulinic acid analogue distinctively improves colorectal carcinoma in vitro and in vivo

D Dutta, B Paul, B Mukherjee, L Mondal, S Sen… - Scientific reports, 2019 - nature.com
Betulinic acid, a plant secondary metabolite, has gained significant attention due to its
antiproliferative activity over a range of cancer cells. A promising betulinic acid analogue …

Betulinic acid: A natural promising anticancer drug, current situation, and future perspectives

M Aswathy, A Vijayan, UD Daimary… - … of Biochemical and …, 2022 - Wiley Online Library
Natural products serve as the single most productive source for the discovery of drugs and
pharmaceutical leads. Among the various chemicals derived from microbes, plants, and …