Investigating the shared genetic architecture between depression and subcortical volumes

M Liu, L Wang, Y Zhang, H Dong, C Wang… - Nature …, 2024 - nature.com
Depression, a widespread and highly heritable mental health condition, profoundly affects
millions of individuals worldwide. Neuroimaging studies have consistently revealed …

Inflammatory bowel disease and rheumatoid arthritis share a common genetic structure

G Cao, Q Luo, Y Wu, G Chen - Frontiers in Immunology, 2024 - frontiersin.org
Background The comorbidity rate of inflammatory bowel disease (IBD) and rheumatoid
arthritis (RA) is high; nevertheless, the reasons behind this high rate remain unclear. Their …

Neuroplasticity of children in autism spectrum disorder

Z Chen, X Wang, S Zhang, F Han - Frontiers in Psychiatry, 2024 - frontiersin.org
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that encompasses a
range of symptoms including difficulties in verbal communication, social interaction, limited …

[HTML][HTML] Charting the shared genetic architecture of Alzheimer's disease, cognition, and educational attainment, and associations with brain development

P Jaholkowski, S Bahrami, V Fominykh… - Neurobiology of …, 2024 - Elsevier
The observation that the risk of developing Alzheimer's disease is reduced in individuals
with high premorbid cognitive functioning, higher educational attainment, and occupational …

Evidence for the gut‐skin axis: Common genetic structures in inflammatory bowel disease and psoriasis

J Guo, Q Luo, C Li, H Liang, Q Cao, Z Li… - Skin Research and …, 2024 - Wiley Online Library
Background Inflammatory bowel disease (IBD) and psoriasis (Ps) are common immune‐
mediated diseases that exhibit clinical comorbidity, possibly due to a common genetic …

Alcohol use disorder and body mass index show genetic pleiotropy and shared neural associations

SG Malone, CN Davis, Z Piserchia, MR Setzer… - medRxiv, 2024 - medrxiv.org
Background: The prevalence of co-occurring heavy alcohol consumption and obesity is
increasing in the United States. Despite neurobiological overlap in the regulation of alcohol …

Is maternal diabetes during pregnancy associated with attention deficit hyperactivity disorder and autism spectrum disorder in children? Insights from individual …

RA Pretorius, D Avraam, M Guxens… - Research …, 2024 - researchportal.murdoch.edu.au
Abstract metabolic disorders gestational diabetes brain development maternal nutrition
Metabolic medicine Nutritional epidemiology Clinical nutrition Behavioural neuroscience …

Involvement of the Wnt Signaling in Methylphenidate (Ritalin) Treatment of ADHD

CM Yde Ohki - 2024 - zora.uzh.ch
As a highly prevalent neurodevelopmental disorder, attention-deficit hyperactivity disorder
(ADHD) mostly affects children and adolescents across the globe, and it is regarded as a …

Shared Genetic Architecture between Schizophrenia and Sex Hormone Traits: A Genomic-Wide Cross-Trait Analysis

X He, Q Ma, J Liu, P Lei, W Lu, Y Liu, X Zhan… - Available at SSRN … - papers.ssrn.com
Background: Sex hormones are involved in schizophrenia pathogenesis; however, their
direction and genetic overlap remain unknown. We aimed to investigate the internal …