Poorly water-soluble drugs are a significant and ongoing issue for the pharmaceutical
industry. An overview of recent developments for the preparation of spray-dried delivery …

Supercritical anti-solvent (SAS) method is a solvent-free approach where supercritical
carbon dioxide (SC-CO 2) is used as anti-solvent and one can control the output particle …

Background: Crystal engineering is dealing with the creation of new structures and new
properties in drug molecules through inter-molecular interactions. Researchers of …

The solubility of Azathioprine, as an immunosuppressive and anti-cancer drug, in
supercritical carbon dioxide (SC-CO 2) was measured for the first time. Under the applied …

In the recent few years, the measurement, correlation, and calculation of solid solubility,
especially drugs, in supercritical fluids have been increased. Evaluation of solubility of a …

In the present work, insulin–chitosan polyelectrolyte complexes associated to lecithin
liposomes were investigated as a new carrier for oral delivery of insulin. The preparation …

When designing particle formation processes, obtaining sufficient knowledge and data
about the solid solute solubility in the super-critical fluids (SCF) is inevitable. Because, this …

Objective: Repaglinide is a well-known FDA approved drug from category of meglitinide;
used for the treatment of diabetes. However, its use is limited because of its poor water …

The novel nano-drug carrier (FDCA-FA-MNPs) was constructed by grafting formyl
deoxycholic acid (FDCA) and folic acid (FA) on the surface of Fe3O4 magnetic nanoparticles …

The major challenge faced by the pharmaceutical industry is the aggregation of drug
nanoparticles. Controlling the surface forces between the particles with the help of …