[HTML][HTML] Acute myeloid leukemia: a comprehensive review and 2016 update

I De Kouchkovsky, M Abdul-Hay - Blood cancer journal, 2016 - nature.com
Acute myeloid leukemia (AML) is the most common acute leukemia in adults, with an
incidence of over 20 000 cases per year in the United States alone. Large chromosomal …

Frontline treatment of acute myeloid leukemia in adults

G Tamamyan, T Kadia, F Ravandi, G Borthakur… - Critical reviews in …, 2017 - Elsevier
Recent years have highlighted significant progress in understanding the underlying genetic
and epigenetic signatures of acute myeloid leukemia (AML). Most importantly, novel …

Clearance of somatic mutations at remission and the risk of relapse in acute myeloid leukemia

K Morita, HM Kantarjian, F Wang, Y Yan… - Journal of Clinical …, 2018 - ascopubs.org
Purpose The aim of the current study was to determine whether the degree of mutation
clearance at remission predicts the risk of relapse in patients with acute myeloid leukemia …

The role of the gastrointestinal microbiome in infectious complications during induction chemotherapy for acute myeloid leukemia

JR Galloway‐Peña, DP Smith, P Sahasrabhojane… - Cancer, 2016 - Wiley Online Library
BACKGROUND Despite increasing data on the impact of the microbiome on cancer, the
dynamics and role of the microbiome in infection during therapy for acute myelogenous …

Acute myeloid leukemia--major progress over four decades and glimpses into the future.

H Kantarjian - American Journal of Hematology, 2016 - europepmc.org
Acute myeloid leukemia--major progress over four decades and glimpses into the future. -
Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu About …

[HTML][HTML] Characterization of oral and gut microbiome temporal variability in hospitalized cancer patients

JR Galloway-Peña, DP Smith, P Sahasrabhojane… - Genome medicine, 2017 - Springer
Background Understanding longitudinal variability of the microbiome in ill patients is critical
to moving microbiome-based measurements and therapeutics into clinical practice …

Therapeutic value of clofarabine in younger and middle-aged (18-65 years) adults with newly diagnosed AML

B Löwenberg, T Pabst, J Maertens… - Blood, The Journal …, 2017 - ashpublications.org
Clofarabine has demonstrated antileukemic activity in acute myeloid leukemia (AML) but
has yet to be critically evaluated in younger adults in the frontline with standard …

Persistence of minimal residual disease assessed by multiparameter flow cytometry is highly prognostic in younger patients with acute myeloid leukemia

F Ravandi, J Jorgensen, G Borthakur, E Jabbour… - Cancer, 2017 - Wiley Online Library
BACKGROUND Predicting outcomes for patients with acute myeloid leukemia (AML) on the
basis of pretreatment predictors has been the cornerstone of management. Posttreatment …

Toward the potential cure of leukemias in the next decade

HM Kantarjian, MJ Keating, EJ Freireich - Cancer, 2018 - Wiley Online Library
Historically, progress in leukemia research has been slow, but it has accelerated recently as
a result of understanding the pathophysiology of leukemias and implementing more effective …

[HTML][HTML] Maintenance therapy in AML

PK Reville, TM Kadia - Frontiers in Oncology, 2021 - frontiersin.org
Recent advances in therapeutics coupled with steady improvements in supportive care for
patients with acute myeloid leukemia (AML) have led to improved outcomes. Despite these …