SIX homeoproteins were first described in Drosophila, where they participate in the Pax-Six-
Eya-Dach (PSED) network with eyeless, eyes absent and dachsund to drive synergistically …

Somite formation is foundational to creating the vertebrate segmental body plan. Here, we
describe three transcriptional trajectories toward somite formation in the early mouse …

Cells with contractile functions are present in almost all metazoans, and so are the related
processes of muscle homeostasis and regeneration. Regeneration itself is a complex …

Cephalochordates and tunicates represent the only two groups of invertebrate chordates,
and extant cephalochordates–commonly known as amphioxus or lancelets–are considered …

The emergence of new structures can often be linked to the evolution of novel cell types that
follows the rewiring of developmental gene regulatory subnetworks. Vertebrates are …

Four SIX homeoproteins display a combinatorial expression throughout embryonic
developmental myogenesis and they modulate the expression of the myogenic regulatory …

The cranial muscle is a critical component in the vertebrate head for a predatory lifestyle.
However, its evolutionary origin and possible segmental nature during embryogenesis have …

The fibroblast growth factor (FGF) signalling pathway plays various roles during vertebrate
embryogenesis, from mesoderm formation to brain patterning. This diversity of functions …

Mineralized skeletal tissues of vertebrates are an evolutionary novelty within the chordate
lineage. While the progenitor cells that contribute to vertebrate skeletal tissues are known to …

The transition to multicellularity is perhaps the best-studied of the “major evolutionary
transitions”. It has occurred independently multiple times within the eukaryotes alone, and …