Helicobacter pylori in Human Stomach: The Inconsistencies in Clinical Outcomes and the Probable Causes

SM Alexander, RJ Retnakumar, D Chouhan… - Frontiers in …, 2021 - frontiersin.org
Pathogenic potentials of the gastric pathogen, Helicobacter pylori, have been proposed,
evaluated, and confirmed by many laboratories for nearly 4 decades since its serendipitous …

Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk

LE Wroblewski, RM Peek Jr… - Clinical microbiology …, 2010 - Am Soc Microbiol
Helicobacter pylori is a gastric pathogen that colonizes approximately 50% of the world's
population. Infection with H. pylori causes chronic inflammation and significantly increases …

Helicobacter pylori: gastric cancer and beyond

DB Polk, RM Peek Jr - Nature reviews cancer, 2010 - nature.com
Helicobacter pylori is the dominant species of the human gastric microbiome, and
colonization causes a persistent inflammatory response. H. pylori-induced gastritis is the …

[HTML][HTML] Helicobacter pylori virulence genes

A Šterbenc, E Jarc, M Poljak… - World journal of …, 2019 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) is one of the most important human pathogens, infecting
approximately half of the global population. Despite its high prevalence, only a subset of H …

Helicobacter pylori and gastrointestinal tract adenocarcinomas

RM Peek Jr, MJ Blaser - Nature Reviews Cancer, 2002 - nature.com
Although gastric adenocarcinoma is associated with the presence of Helicobacter pylori in
the stomach, only a small fraction of colonized individuals develop this common malignancy …

[HTML][HTML] Review of atrophic gastritis and intestinal metaplasia as a premalignant lesion of gastric cancer

YH Park, N Kim - Journal of cancer prevention, 2015 - ncbi.nlm.nih.gov
Atrophic gastritis (AG) and intestinal metaplasia (IM) are the main precursor lesions of
gastric cancer as the incidence of gastric cancer increases in the gastric mucosa involved …

Helicobacter pylori in health and disease

TL Cover, MJ Blaser - Gastroenterology, 2009 - Elsevier
Helicobacter pylori is highly adapted for colonization of the human stomach and is present in
about half of the human population. When present, H pylori is usually the numerically …

Helicobacter pylori Detection and Antimicrobial Susceptibility Testing

F Mégraud, P Lehours - Clinical microbiology reviews, 2007 - Am Soc Microbiol
The discovery of Helicobacter pylori in 1982 was the starting point of a revolution concerning
the concepts and management of gastroduodenal diseases. It is now well accepted that the …

[HTML][HTML] Infection with Helicobacter pylori

IARC Working Group on the Evaluation of … - … , liver flukes and …, 1994 - ncbi.nlm.nih.gov
The presence of spiral-shaped bacteria on human gastric mucosa was first recognized
nearly one hundred years ago (Pel, 1899). These bacteria were isolated for the first time in …

Vacuolating cytotoxin A (VacA), a key toxin for Helicobacter pylori pathogenesis

SL Palframan, T Kwok, K Gabriel - Frontiers in cellular and infection …, 2012 - frontiersin.org
More than 50% of the world's population is infected with Helicobacter pylori (H. pylori).
Chronic infection with this Gram-negative pathogen is associated with the development of …