Physical activity is one of the modifiable factors of cognitive decline and dementia with the
strongest evidence. Although many influential reviews have illustrated the neurobiological …

The idea of central nervous system as one-man band favoring neurons is long gone. Now
we all are aware that neurons and neuroglia are team players and constant communication …

Disrupted hippocampal performance underlies psychiatric comorbidities and cognitive
impairments in patients with neurodegenerative disorders. To understand the contribution of …

Adult hippocampal neurogenesis (AHN) drops sharply during early stages of Alzheimer's
disease (AD), via unknown mechanisms, and correlates with cognitive status in AD patients …

Mounting evidence has firmly established that low levels of cardiorespiratory fitness (CRF)
are associated with a high risk of cardiovascular disease, all-cause mortality, and mortality …

Convincing evidence has repeatedly shown that new neurons are produced in the
mammalian brain into adulthood. Adult neurogenesis has been best described in the …

Major Depressive Disorder (MDD) is a leading cause of disability worldwide, creating a high
medical and socioeconomic burden. There is a growing interest in the biological …

In the adult rodent brain, neural stem cells (NSCs) persist in the ventricular-subventricular
zone (V-SVZ) and the subgranular zone (SGZ), which are specialized niches in which young …

Endothelial cells that line capillaries are not just passive conduits for delivering blood.
Tissue-specific endothelium establishes specialized vascular niches that deploy sets of …

Of the neurogenic zones in the adult brain, adult hippocampal neurogenesis attracts the
most attention, because it is involved in higher cognitive function, most notably memory …