Coronary stents: current status

S Garg, PW Serruys - Journal of the American College of Cardiology, 2010 - jacc.org
Coronary artery stents revolutionized the practice of interventional cardiology after they were
first introduced in the mid-1980s. Since then, there have been significant developments in …

The role of genetic polymorphism and other factors on clopidogrel resistance (CR) in an Asian population with coronary heart disease (CHD)

MA Akkaif, NAA Daud, A Sha'aban, ML Ng… - Molecules, 2021 - mdpi.com
Clopidogrel is a widely-used antiplatelet drug. It is important for the treatment and prevention
of coronary heart disease. Clopidogrel can effectively reduce platelet activity and therefore …

ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the …

Authors/Task Force Members, CW Hamm… - European heart …, 2011 - academic.oup.com
ESC Guidelines 3002 recommendations. To implement the guidelines, condensed pocket
guidelines versions, summary slides, booklets with essential messages, and an electronic …

Antiplatelet therapies for the treatment of cardiovascular disease

AD Michelson - Nature Reviews Drug Discovery, 2010 - nature.com
Antiplatelet therapy has been successful in reducing mortality and morbidity in acute
myocardial infarction. Recent advances in understanding the molecular basis of the role of …

Cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting are predicted by residual platelet reactivity to …

R Marcucci, AM Gori, R Paniccia, B Giusti, S Valente… - Circulation, 2009 - Am Heart Assoc
Background—The clinical impact of platelet aggregation assessed by point-of-care assays is
unknown. We sought to evaluate whether high residual platelet reactivity (RPR) to ADP …

Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel

JM Siller-Matula, AO Spiel, IM Lang, G Kreiner… - American heart …, 2009 - Elsevier
BACKGROUND: Clopidogrel is activated by CYP2C19, which also metabolizes proton pump
inhibitors (PPI). As proton pump inhibitors (PPI) are metabolized to varying degrees by …

Impact of CYP2C19 variant genotypes on clinical efficacy of antiplatelet treatment with clopidogrel: systematic review and meta-analysis

T Bauer, HJ Bouman, JW van Werkum, NF Ford… - Bmj, 2011 - bmj.com
Objective To evaluate the accumulated information from genetic association studies
investigating the impact of variants of the cytochrome P450 (CYP) 2C19 genotype on the …

Antiplatelet drugs: a review of their pharmacology and management in the perioperative period

R Hall, CD Mazer - Anesthesia & Analgesia, 2011 - journals.lww.com
In the normal course of the delivery of care, anesthesiologists encounter many patients who
are receiving drugs that affect platelet function as a fundamental part of primary and …

Interindividual variability in the response to oral antiplatelet drugs: a position paper of the Working Group on antiplatelet drugs resistance appointed by the Section of …

W Kuliczkowski, A Witkowski, L Polonski… - European heart …, 2009 - academic.oup.com
Oral antiplatelet drugs are a cornerstone of modern pharmacotherapy in cardiovascular
atherothrombotic diseases. The efficacy of acetylsalicylic acid (ASA, aspirin) and clopidogrel …

Point-of-care measurement of clopidogrel responsiveness predicts clinical outcome in patients undergoing percutaneous coronary intervention: results of the …

G Patti, A Nusca, F Mangiacapra, L Gatto… - Journal of the American …, 2008 - jacc.org
Objectives: The aim of this study was to evaluate the correlation of point-of-care
measurement of platelet inhibition with clinical outcome in patients undergoing …