Given the distinctive characteristics of both epilepsy and antiepileptic drugs (AEDs),
therapeutic drug monitoring (TDM) can make a significant contribution to the field of …

In the past twenty years, 14 new antiepileptic drugs have been approved for use in the
United States and/or Europe. These drugs are eslicarbazepine acetate, felbamate …

In the past twenty-one years, 17 new antiepileptic drugs have been approved for use in the
United States and/or Europe. These drugs are clobazam, ezogabine (retigabine) …

Therapeutic drug monitoring (TDM) of antiepileptic drugs (AEDs) has been recognized as a
useful tool in management of epilepsy. We developed a simple analytical method for …

1.5 Uses and applications Topiramate is classified as a sulfamate-substituted
monosaccharide and is known as an anticonvulsant or antiepileptic drug. It is used alone or …

Therapeutic drug monitoring (TDM) may be very useful in the clinical management of
antiepileptic drug therapy for multiple reasons, such as individual variability, metabolism …

Two highly sensitive, simple and selective spectrophotometric and spectrofluorimetric
assays have been investigated for the analysis of ezogabine, levetiracetam and topiramate …

Topiramate has no ultraviolet, visible or fluorescence absorption. Analysis of the drug in
human serum has been reported by high performance liquid chromatography (HPLC) with …

Pre-column derivatization methods for high performance liquid chromatographic assay of
specific pharmaceutical agents using 9-fluorenylmethyl chloroformate (FMOC-Cl) have …

This paper reviews analytical methods, instrumental developments and applications for
derivatization of amines and amino acids with 7-Chloro-4-nitrobenzoxadiazole (NBD-Cl) …