RNA packaging into extracellular vesicles: An orchestra of RNA‐binding proteins?

F Fabbiano, J Corsi, E Gurrieri… - Journal of …, 2020 - Wiley Online Library
Extracellular vesicles (EVs) are heterogeneous membranous particles released from the
cells through different biogenetic and secretory mechanisms. We now conceive EVs as …

Current challenges and opportunities in treating glioblastoma

A Shergalis, A Bankhead III, U Luesakul… - Pharmacological …, 2018 - Elsevier
Glioblastoma multiforme (GBM), the most common and aggressive primary brain tumor, has
a high mortality rate despite extensive efforts to develop new treatments. GBM exhibits both …

Transcriptome‐level discovery of survival‐associated biomarkers and therapy targets in non‐small‐cell lung cancer

B Győrffy - British Journal of Pharmacology, 2024 - Wiley Online Library
Abstract Background and Purpose Survival rate of patients with lung cancer has increased
by over 60% in the recent two decades. With longer survival, the identification of genes …

Chemotherapy-induced S100A10 recruits KDM6A to facilitate OCT4-mediated breast cancer stemness

H Lu, Y Xie, L Tran, J Lan, Y Yang… - The Journal of …, 2020 - Am Soc Clin Investig
Breast cancer stem cells (BCSCs) play a critical role in cancer recurrence and metastasis.
Chemotherapy induces BCSC specification through increased expression of pluripotency …

Annexins—a family of proteins with distinctive tastes for cell signaling and membrane dynamics

V Gerke, FNE Gavins, M Geisow, T Grewal… - Nature …, 2024 - nature.com
Annexins are cytosolic proteins with conserved three-dimensional structures that bind acidic
phospholipids in cellular membranes at elevated Ca2+ levels. Through this they act as Ca2+ …

HPV entry into cells

P Aksoy, EY Gottschalk, PI Meneses - Mutation Research/Reviews in …, 2017 - Elsevier
Human papillomavirus (HPV) is a sexually transmitted virus responsible for the development
of cervical cancer, anal cancer, head and throat cancers, as well as genital area warts. A …

[HTML][HTML] Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway

LJ Jia, M Rafiq, L Radosa, P Hortschansky, C Cunha… - Cell Host & Microbe, 2023 - cell.com
The decision whether endosomes enter the degradative or recycling pathway in mammalian
cells is of fundamental importance for pathogen killing, and its malfunctioning has …

Annexins in translational research: hidden treasures to be found

S Schloer, D Pajonczyk, U Rescher - International journal of molecular …, 2018 - mdpi.com
The vertebrate annexin superfamily (AnxA) consists of 12 members of a calcium (Ca2+) and
phospholipid binding protein family which share a high structural homology. In keeping with …

The annexin A2/S100A10 complex: the mutualistic symbiosis of two distinct proteins

A Bharadwaj, E Kempster, DM Waisman - Biomolecules, 2021 - mdpi.com
Mutualistic symbiosis refers to the symbiotic relationship between individuals of different
species in which both individuals benefit from the association. S100A10, a member of the …

[HTML][HTML] The long and winding road: human papillomavirus entry and subcellular trafficking

MA Ozbun, SK Campos - Current opinion in virology, 2021 - Elsevier
Human papillomaviruses (HPVs) infect and replicate in differentiating mucosal and
cutaneous epithelium. Most HPV infections are asymptomatic or cause transient benign …