Lipopolysaccharide (LPS) is a crucial constituent of the outer membrane of most Gram-
negative bacteria, playing a fundamental role in the protection of bacteria from …

The microbiota—the collection of microorganisms that live within and on all mammals—
provides crucial signals for the development and function of the immune system. Increased …

The functional maturation and preservation of hepatic cells derived from human induced
pluripotent stem cells (hiPSCs) are essential to personalized in vitro drug screening and …

Metastasis is the leading cause of death for colorectal cancer (CRC) patients, and the
spreading tumor cells adhesion to endothelial cells is a critical step for extravasation and …

The urogenital tract is a complex environment composed of many different types of epithelial
tissues and innate immune cells that sample the surrounding milieu. As a host-adapted …

Intestinal microbiota is an element of the bacterial ecosystem in all mammalian organisms.
These microorganisms play a very important part in the development, functioning, and …

The mammalian gastrointestinal tract and associated mucosal immune system harbor a
large repertoire of metabolites of prokaryotic and eukaryotic origin that play important roles …

Sepsis is defined as life-threatening organ dysfunction caused by the dysregulated host
response to infection. Despite serious mortality and morbidity, no sepsis-specific drugs exist …

The molecular bases of how host genetic variation impacts the gut microbiome remain
largely unknown. Here we used a genetically diverse mouse population and applied …

Crohn's disease (CD) and Ulcerative colitis (UC) are grouped as Inflammatory Bowel
Diseases (IBD). The IBD is associated to a multifaceted interplay between immunologic …