TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells
The signalling pathways that maintain primed human pluripotent stem cells (hPSCs) have
been well characterised, revealing a critical role for TGFβ/Activin/Nodal signalling. In …
been well characterised, revealing a critical role for TGFβ/Activin/Nodal signalling. In …
Single-cell RNA sequencing of human embryonic stem cell differentiation delineates adverse effects of nicotine on embryonic development
Nicotine, the main chemical constituent of tobacco, is highly detrimental to the developing
fetus by increasing the risk of gestational complications and organ disorders. The effects of …
fetus by increasing the risk of gestational complications and organ disorders. The effects of …
Network approaches for charting the transcriptomic and epigenetic landscape of the developmental origins of health and disease
SD Lombardo, IF Wangsaputra, J Menche, A Stevens - Genes, 2022 - mdpi.com
The early developmental phase is of critical importance for human health and disease later
in life. To decipher the molecular mechanisms at play, current biomedical research is …
in life. To decipher the molecular mechanisms at play, current biomedical research is …
[HTML][HTML] Comparative single-cell transcriptomic profiles of human androgenotes and parthenogenotes during early development
P de Castro, X Vendrell, L Escrich, N Grau… - Fertility and …, 2023 - Elsevier
Objective To unravel the differential transcriptomic behavior of human androgenotes (AGs)
and parthenogenotes (PGs) throughout the first cell cycles, analyze the differential …
and parthenogenotes (PGs) throughout the first cell cycles, analyze the differential …
[PDF][PDF] and Joseph C. Wu
Nicotine, the main chemical constituent of tobacco, is highly detrimental to the developing
fetus by increasing the risk of gestational complications and organ disorders. The effects of …
fetus by increasing the risk of gestational complications and organ disorders. The effects of …