Peptides mediate cancer progression favoring the mitogenesis, migration, and invasion of
tumor cells, promoting metastasis and anti-apoptotic mechanisms, and facilitating …

Abstract Purposeof Review In this review, we will summarize the effects of these
perioperative anesthetics and anesthetic interventions on the immune system and …

To investigate the effects of different anesthetic methods on postoperative immune function
in patients undergoing gastrointestinal tumor resection. Ninety patients undergoing …

The κ‑opioid receptor (KOR) is one of the primary receptors of opioids and serves a vital role
in the regulation of pain, anesthesia, addiction and other pathological and physiological …

Cancer pain, especially the moderate-to-severe pain experienced by patients with advanced
cancer, is still one of the most challenging clinical problems. The current mainstream …

Abstract Purpose of Review Opioids are still the most effective and widely used treatments
for acute and chronic pain in cancer patients. This review focuses on the impact of opioids …

The discovery of novel therapeutic targets, defined as proteins which drugs can interact with
to induce therapeutic benefits, typically represent the first and most important step of drug …

Background Opioids are widely used during primary debulking surgery (PDS) for ovarian
cancers, and a high mu-opioid receptor (MOR) expression predicts worse cancer outcomes …

Background Numerous reports contend opioids can augment or inhibit malignancy. At
present, there is no consensus on the risk or benefit posed by opioids on malignancy or …

Pain is one of the most common symptoms in patients with cancer. Pain not only negatively
affects the quality of life of patients with cancer, but it has also been associated with reduced …