Chronic inflammation is the main feature of many long-term inflammatory diseases such as
autoimmune diseases, metabolic disorders, and cancer. There is a growing number of …

Although anti-angiogenic therapies (AATs) have some effects against multiple malignancies,
they are limited by subsequent tumor vasculogenesis and progression. To investigate the …

Rapidly growing tumors often experience hypoxia and nutrient (eg, glucose) deficiency
because of poor vascularization. Tumor cells respond to the cytotoxic effects of such …

Adipokines have been reported to be involved in the regulation of various physiological
processes, including the immune response. Rheumatoid arthritis (RA) is an example of a …

Endothelial progenitor cells (EPCs) promote angiogenesis and are therefore key
contributors to a wide variety of angiogenesis-related autoimmune diseases such as …

CD13, an ectoenzyme on myeloid and stromal cells, also circulates as a shed, soluble
protein (sCD13) with powerful chemoattractant, angiogenic, and arthritogenic properties …

Cancer may arise from dedifferentiation of mature cells or maturation-arrested stem cells.
Previously we reported that definitive endoderm from which liver was derived, expressed …

The complex microenvironment of persistent inflammation and bacterial infection is a major
challenge in chronic diabetic wounds. The development of nanozymes capable of efficiently …

Fucosylation is a biological process that plays a critical role in multiple cellular functions
from cell adhesion to immune regulation. Fucosyltransferases (FUTs) mediate fucosylation …

The presence of the blood group H2 antigen on the membrane of red blood cells determines
blood type O in individuals and this H2 antigen serves as a precursor to the A and B …