With the aging population and its rapidly increasing prevalence, dementia has become an
important public health concern in developed and developing countries. To date, the …

Summary Abstract Memantine (Ebixa®, Axura®, Namenda®, Akatinol®) is a moderate-
affinity, uncompetitive, voltage-dependent, NMDA-receptor antagonist with fast on/off …

Alzheimer's disease (AD) is becoming an increasingly heavy burden on the society of
developed countries, and physicians now face the challenge of providing efficient treatment …

CYP2B6 metabolizes a number of drug substrates, that are usually non-planar, neutral or
weakly basic, fairly lipophilic with one or two hydrogen bond acceptors, on which it catalyses …

The pathogenic processes driving Alzheimer's disease (AD) are complex. An incomplete
understanding of underlying disease mechanisms has presented insurmountable obstacles …

Alzheimer's disease (AD) is a major problem of health and disability, with a relevant
economic impact on our society. Despite important advances in pathogenesis, diagnosis …

Symptomatic interventions for patients with dementia involve anti-dementia drugs to improve
cognition, psychotropic drugs for the treatment of behavioral disorders (BDs), and different …

Abstract Neurodegenerative disorders (NDDs)(Alzheimer's disease, Parkinson's disease)
represent major problems of health in developed countries, with important psychosocial …

Introduction: As the world's population ages, the incidence of Alzheimer's disease (AD) is
projected to double every 20 years. Understanding the pathogenesis of AD and developing …

Abstract The Measurement and Treatment Research to Improve Cognition in Schizophrenia
(MATRICS) and Treatment Units for Research on Neurocognition and Schizophrenia …